نتایج جستجو برای: 371
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The present study examined RTI-371 [3β-(4-methylphenyl)-2β-[3-(4-chlorophenyl)-isoxazol-5-yl]tropane], a phenyltropane cocaine analog with effects distinct from cocaine, and assessed potential mechanisms for those effects by comparison with its constitutional isomer, RTI-336 [3β-(4-chlorophenyl)-2β-[3-(4-methylphenyl)-isoxazol-5-yl]tropane]. In mice, RTI-371 was less effective than cocaine and ...
A novel nonnucleoside inhibitor of hepatitis C virus (HCV) RNA-dependent RNA polymerase (RdRp), [(1R)-5-cyano-8-methyl-1-propyl-1,3,4,9-tetrahydropyano[3,4-b]indol-1-yl] acetic acid (HCV-371), was discovered through high-throughput screening followed by chemical optimization. HCV-371 displayed broad inhibitory activities against the NS5B RdRp enzyme, with 50% inhibitory concentrations ranging f...
..................................................................................................................................................... 367 INTRODUCTION .............................................................................................................................................. 367 PAX GENES, PAIRED DOMAINS AND PAX HOMEODOMAINS .......................................
371 2013 Phil. Trans. R. Soc. A Julian M. Allwood, Michael F. Ashby, Timothy G. Gutowski and Ernst Worrell with less material production Material efficiency: providing material services References html#related-urls http://rsta.royalsocietypublishing.org/content/371/1986/20120496.full. Article cited in: 96.full.html#ref-list-1 http://rsta.royalsocietypublishing.org/content/371/1986/201204 This a...
C.Dechanet1,, T. Anahory1, J.C.Mathieu Daude2, X.Quantin3, L. Reyftmann1, S.Hamamah1, B. Hedon1, and H.Dechaud1 Department of Medicine and Biology of Reproduction, Hôpital Arnaud de Villeneuve, 371 Avenue du Doyen Gaston Giraud, 34 295 Montpellier Cedex 5, France Department of Toxicology, Hôpital Lapeyronie, 371 Avenue du Doyen Gaston Giraud, 34 295 Montpellier Cedex 5, France Department of Tho...
BACKGROUND Micro RNAs-371-372-373 (miRNAs-371-373), originating from the same pri-miRNA transcript, are reported to be upregulated in hepatocellular carcinoma (HCC) and to be related to the regulation of hepatitis B virus (HBV) infection. Our study investigated whether pri-miRNAs-371-373 polymorphisms are associated with the risk of HCC occurrence and HBV clearance. METHODS Genetic variations...
Expression of the mouse miR-290-295 cluster and its miR-371-373 homolog in human is restricted to early embryos, primordial germ cells, the germ line stem cell compartment of the adult testis and to stem cell lines derived from the early embryonic lineages. Sequencing data suggest considerable seed diversification between the seven homologous pre-miRNAs of miR-290-295 but it is not clear if all...
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