نتایج جستجو برای: 365
تعداد نتایج: 6734 فیلتر نتایج به سال:
Bu çalışmanın amacı Tarık Demirkan’ın Her Güne Bir Masal isimli eserinin değerler eğitimine katkısını incelemektir. Çalışma “nitel araştırma yöntemi” ne uygun olarak yapılmıştır. Çalışmada nitel desenlerinden “doküman incelemesi” kullanılmıştır. Verilerin toplanmasında araştırmacı tarafından geliştirilen “Değer İnceleme Formu” Çalışmanın materyalini eserinde yer alan 365 masal metni oluşturmakt...
The expression levels of miR-365 vary in different malignancies. Herein, we found that miR-365 was overexpressed in both cells and clinical specimens of cutaneous squamous cell carcinoma (SCC). We demonstrated that the HaCaT(pre-miR-365-2) cell line, which overexpressed miR-365, could induce subcutaneous tumors in vivo. Antagomir-365, an anti-miR-365 oligonucleotide, inhibited cutaneous tumor f...
MicroRNA-365 (miR-365) plays crucial roles in regulating cell proliferation, apoptosis and differentiation in various cell types. However, its function in vascular smooth muscle cells (VSMCs) is largely unknown. In our study, we found miR-365 was highly expressed in adult rat carotid arteries, but was significantly decreased in rat carotid arteries after balloon injury, a process involving neoi...
Hepatocellular carcinoma (HCC) is currently ranked as the third leading cause of cancer-related mortality worldwide. microRNAs (miRs) serve important roles in the development and progression of HCC. miR-365 has been demonstrated to function as a tumor suppressor in several types of cancer, including HCC; however, the mechanisms by which miR-365 regulates HCC apoptosis remains to be elucidated. ...
Finite and Infinite Sets. Countability. Proof Techniques (Chapter 1, Sections 1.4, 1.5) Finite sets finite number of elements can be counted Infinite sets infinite number of elements Equinumerous sets: Sets A and B are equinumerous if there is a bijection f : A → B E.G.: A = {1,2,3}, B = {a,b,c} Countably infinite sets: A set is countably infinite if it is equinumerous with N (the set of natura...
MicroRNAs (miRNAs) have important roles in the initiation and progression of human cancer, including breast cancer. We evaluated miR‑365 expression in breast cancer tissues, and investigated its effects on cell growth, cell cycle, cell invasion, and expression of its target gene ADAMTS-1. miR‑365 expression levels were analyzed in breast cancer tissues and adjacent normal tissues using qRT-PCR....
MircroRNA functions as tumor suppressor or promoter in hepatocellular carcinoma (HCC). Researchers have found that miR-365 expression was lower in HCC tissues compared with that in adjacent normal tissues. However, its prognostic significance and anti-proliferation effect in HCC remain to be clarified. In this study, we firstly found that miR-365 expression was lower in HCC tissues compared wit...
Glucocorticoid administration is the leading cause of secondary osteoporosis. In this study, we tested the hypotheses that histone deacetylase 4 (HDAC4) is associated with glucocorticoid-induced bone loss and that HDAC4 dependent bone loss can be ameliorated by miRNA-365. Our previous studies showed that miR-365 mediates mechanical stimulation of chondrocyte proliferation and differentiation by...
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