نتایج جستجو برای: 3 dihydroquinazolin 41h ones

تعداد نتایج: 1909670  

2012
Hayun Sumi Hudiyono Muhammad Hanafi Arry Yanuar

Some novel 3-phenyl-2-[(E)-2-phenylethenyl]-3,4-dihydroquinazolin-4-one derivatives possessing para-sulfonamides groups on the phenyl ring of the 2-phenylethenyl moiety have been synthesized and their COX-2 inhibitory activity evaluated. The stuctures of the synthesized compounds were confirmed  on the basis of  FT-IR, 1H-NMR, 13C-NMR and mass spectral data. The COX-2 inhibition screening assay...

Journal: :iranian journal of catalysis 2012
arash shokrolahi abbas zali mohammad ali zarei karim esmaeilpour

a simple and efficient procedure has been developed for the synthesis of 2,3-dihydroquinazolin-4(1h)-ones derivatives under solvent-free conditions. this method uses the condensation of isatoic anhydride, aldehydes, and amines in the presence of a catalytic amount sulfonated porous carbon (spc). one of the important advantages of the new method is that the spc could be recycled and reused.

Journal: :Journal of enzyme inhibition and medicinal chemistry 2016
Ibrahim A Al-Suwaidan Alaa A-M Abdel-Aziz Taghreed Z Shawer Rezk R Ayyad Amer M Alanazi Ahmad M El-Morsy Menshawy A Mohamed Naglaa I Abdel-Aziz Magda A-A El-Sayed Adel S El-Azab

A novel series of 3-benzyl-substituted-4(3H)-quinazolinones were designed, synthesized and evaluated for their in vitro antitumor activity. The results of this study demonstrated that 2-(3-benzyl-6-methyl-4-oxo-3,4-dihydroquinazolin-2-ylthio)-N-(3,4,5-trimethoxyphenyl)acetamide, 2-(3-benzyl-6,7-dimethoxy-4-oxo-3,4-dihydroquinazolin-2-ylthio)-N-(3,4,5-trimethoxyphenyl)acetamide and 3-(3-benzyl-6...

Abbas Zali Arash Shokrolahi Karim Esmaeilpour Mohammad Ali Zarei

A simple and efficient procedure has been developed for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones derivatives under solvent-free conditions. This method uses the condensation of isatoic anhydride, aldehydes, and amines in the presence of a catalytic amount Sulfonated Porous Carbon (SPC). One of the important advantages of the new method is that the SPC could be recycled and reused.

Abbas Zali Arash Shokrolahi Karim Esmaeilpour Mohammad Ali Zarei

A simple and efficient procedure has been developed for the synthesis of 2,3-dihydroquinazolin-4(1H)-ones derivatives under solvent-free conditions. This method uses the condensation of isatoic anhydride, aldehydes, and amines in the presence of a catalytic amount Sulfonated Porous Carbon (SPC). One of the important advantages of the new method is that the SPC could be recycled and reused.

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