The purpose of this study is to evaluate the therapeutic results of small hepatocellular carcinoma (HCC) treated with hyperfractionated three-dimensional conformal radiotherapy (3-D conformal RT). This retrospective study was to review 39 small HCC (tumor ≤ 5 cm in size) patients who had been treated with hyperfractionated 3-D conformal RT from October 1999 to December 2000. The mean age was 59...

A male patient, aged 33, was treated at the Clinic for Oncology, Hematology and Radiotherapy at the University Clinical Center, Tuzla, with the diagnosis of diffuse large B-cell lymphoma. Conformal radiotherapy was conducted on the region of the epipharynx, oropharynx and lymph nodes of the neck on both sides (1). The target volume included the following: the clinical target volume (CTV) of the...

BACKGROUND According to the literature, performance status, stage-tumor dimension and nodal status, weight loss, were the most important prognostic factors for survival in patients with locally advanced non-small cell lung cancer. AIM To evaluate the treatment results and the prognostic variables in our patients treated with sequential and concurrent chemoradiotherapy. MATERIAL AND METHODS ...

The aim of the study was to compare the survival impact of concurrent versus sequential treatment with radiotherapy and chemotherapy in inoperable stage III non-small cell lung cancer (NSCLC). 85 patients were randomly assigned to one of the two treatment groups. In the sequential group, 45 patients had previously received sequential chemotherapy with 4 cycles of carboplatine and etoposide foll...

Objective: To investigate the feasibility of hippocampal-sparing whole-brain radiotherapy and reduction in neurocognitive function impairment after radiotherapy. Methods: Forty-three patients with brain metastases were selected. Whole-brain radiotherapy was performed in 22 patients, with 3-dimensional conformal radiotherapy in parallel opposed fields. Twenty-one patients had significant differe...

AIMS AND BACKGROUND Radiotherapy represents one of the basic therapeutic methods in treatment of localized carcinoma of the prostate. Optimal irradiation dose is the cornerstone of a successful treatment. Along with local control of the disease and overall survival of the patient, possible acute and long-term side effects need to be monitored very closely. METHODS A non-randomized prospective...

An algorithm has been developed to calculate the collimator jaw motions required to generate intensity-modulated fields far use in conformal radiotherapy. The dynamic technique allows arbitrary intensity profiles to he generated using a single unidirectional sweep of the collimators. The collimator jaws have independent motion, so that an aperture of variable width is scanned across the field. ...

BACKGROUND & OBJECTIVE Radiotherapy and chemotherapy are major therapies for locally advanced pancreatic cancer. This study was to evaluate the efficacy of three-dimensional conformal gamma-knife radiotherapy combined with thermochemotherapy on locally advanced pancreatic cancer. METHODS From December 2001 to January 2006, 75 patients with locally advanced pancreatic cancer were divided into ...