نتایج جستجو برای: 3 β hydroxybutyrate

تعداد نتایج: 1959602  

Journal: :Metabolites 2023

Opposing evidence exists for the source of hydrogen ions (H+) during ketoacidosis. Organic and computational chemistry using dissociation constants alpha equations all pertinent ionizable metabolites were used to (1) document atomic changes in chemical reactions ketogenesis ketolysis (2) identify sources quantify added fractional (~) H+ exchange (~H+e). All computations performed pH conditions ...

2018
Jingzhu Zhang Xinhui Li Yahao Ren Yue Zhao Aiping Xing Congmin Jiang Yanqiu Chen Li An

Intermittent fasting has been demonstrated to protect against Alzheimer's disease (AD), however, the mechanism is unclear. Histone acetylation and lipoprotein lipase (LPL) are involved in AD progression. Importantly, LPL has been documented to be regulated by histone deacetylases (HDACs) inhibitors (increase histone acetylation level) in adipocyte and mesenchymal stem cells, or by fasting in ad...

Journal: :FEMS microbiology letters 2015
Margreet J Oosterkamp Sjef Boeren Siavash Atashgahi Caroline M Plugge Peter J Schaap Alfons J M Stams

Alicycliphilus denitrificans strain BC grows anaerobically on acetone with nitrate as electron acceptor. Comparative proteomics of cultures of A. denitrificans strain BC grown on either acetone or acetate with nitrate was performed to study the enzymes involved in the acetone degradation pathway. In the proposed acetone degradation pathway, an acetone carboxylase converts acetone to acetoacetat...

2012
Youichi Yanagawa Yohei Hirano Masaaki Takemoto Tetsuhiro Takei Toshitaka Ito Toshiaki Iba

Alcoholic Ketoacidosis (AKA) is an acute metabolic acidosis that typically occurs in people who chronically abuse alcohol and have a recent history of binge drinking, little or no food intake and persistent vomiting [1]. AKA is a result of starvation with glycogen depletion and counter-regulatory hormone production, an increased ratio of Nicotinamide Adenine Dinucleotide (NADH) to Nicotinamide ...

Journal: :American Journal of Clinical Pathology 1997

Journal: :Annual Review of Nutrition 2017

Journal: :Environmental health and preventive medicine 2012
Yuriko Higashino-Matsui Ken Shirato Yuko Suzuki Yu Kawashima Yui Someya Shogo Sato Akira Shiraishi Manabu Jinde Akiko Matsumoto Hisashi Ideno Kaoru Tachiyashiki Kazuhiko Imaizumi

OBJECTIVE The age-related effects of fasting on lipolysis, the production of ketone bodies, and plasma insulin levels were studied in male 3-, 8-, and 32-week-old Sprague-Dawley rats. METHODS The rats were divided into fasting and control groups. The 3-, 8- and 32-week-old rats tolerated fasting for 2, 5, and 12 days, respectively. RESULTS Fasting markedly reduced the weights of perirenal a...

2016
Sama F Sleiman Jeffrey Henry Rami Al-Haddad Lauretta El Hayek Edwina Abou Haidar Thomas Stringer Devyani Ulja Saravanan S Karuppagounder Edward B Holson Rajiv R Ratan Ipe Ninan Moses V Chao

Exercise induces beneficial responses in the brain, which is accompanied by an increase in BDNF, a trophic factor associated with cognitive improvement and the alleviation of depression and anxiety. However, the exact mechanisms whereby physical exercise produces an induction in brain Bdnf gene expression are not well understood. While pharmacological doses of HDAC inhibitors exert positive eff...

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