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PURPOSE To determine the effects of creatine supplementation on blood lactate during incremental cycling exercise. METHODS Thirteen male subjects (M ± SD 23 ± 2 yr, 178.0 ± 8.1 cm, 86.3 ± 16.0 kg, 24% ± 9% body fat) performed a maximal, incremental cycling test to exhaustion before (Pre) and after (Post) 6 d of creatine supplementation (4 doses/d of 5 g creatine + 15 g glucose). Blood lactate...
Do the fundamental constants vary in the course of the cosmological evolution ? Abstract – We estimate the cosmological variation of the proton-to-electron mass ratio µ = m p /m e by measuring the wavelengths of molecular hydrogen transitions in the early universe. The analysis is performed using high spectral resolution observations (F W HM ≈ 7 km/s) of two damped Lyman-α systems at z abs = 2....
Do the fundamental constants vary in the course of the cosmological evolution ? Abstract – We estimate the cosmological variation of the proton-to-electron mass ratio µ = m p /m e by measuring the wavelengths of molecular hydrogen transitions in the early universe. The analysis is performed using high spectral resolution observations (F W HM ≈ 7 km/s) of two damped Lyman-α systems at z abs = 2....
I In a previous publication,8 we reported for the older Type II Sigma ribonuclease a value of An/c = 0.185 ml/gm. We now correct this value to 0.187 ml/gm; however, the precision cannot be evaluated with confidence. 8 Clarke, A. M., D. W. Kupke, and J. W. Beams, J. Phys. Chem., 67, 929 (1963). 9 McMeekin, T. L., private communication. 10 Reithel, F. J., and J. D. Sakura, J. Phys. Chem., 67, 249...
abstract venlafaxine, 1–[2–(dimethylamino)–1–(4–methoxyphenyl) ethyl]cyclohexanol hydrochloride is a novel non-tricyclic antidepressant. venlafaxine is a second generation antidepressant drug, has a neuropharmacologic profile distinct from that of existing antidepressants including tricyclic compounds, selective serotonin reuptake inhibitors and monoamine oxidase inhibitors. venlafaxine impart...
section{introduction} the concept of {sl cartan geometry} appeared at the beginning of the twentieth century, when {e}lie cartan was working on the so-called {sl equivalence problem}, the aim of which is to determine whether two given geometric structures can be mapped bijectively onto each other by some diffeomorphism. this problem can be considered in many different contexts, such as ...
Citation for published version: Chen, DL, Cheriyan, J, Chilvers, ER, Choudhury, G, Coello, C, Connell, M, Fisk, M, Groves, AM, Gunn, RN, Holman, BF, Hutton, BF, Lee, S, MacNee, W, Mohan, D, Parr, D, Subramanian, D, Tal-Singer, R, Thielemans, K, van Beek, EJR, Vass, L, Wellen, JW, Wilkinson, I & Wilson, FJ 2017, 'Quantification of Lung PET Images: Challenges and Opportunities' Journal of Nuclear...
A fundamental feature of any drug designed to treat a disease of the central nervous system is the ability to cross the blood-brain barrier. Passage across the blood-brain barrier of AIT-082, a cognitive enhancer, was investigated in mice. [(14)C]AIT-082 crossed the blood-brain barrier in young male Swiss-Webster mice with a mean influx constant (K(i)) of 0.6 +/- 0.2 microl g(-1) min(-1). Furth...
6 F. Jacob, Virology, 1, 207, 1955. P. E. Hartman, in Symposium on the Chemical Basis of Heredity, ed. W. D. McElroy and B. Glass (Baltimore: Johns Hopkins Press, 1957), p. 408. 8 M. L. Morse, E. M. Lederberg, and J. Lederberg, Genetics, 41, 142, 1956. 9 M. L. Morse, E. M. Lederberg, and J. Lederberg, ibid., 41, 758, 1956. 10 A. Campbell, Virology, 4, 366, 1957. 11 W. Arber, G. Kellenberger, an...
Metabotropic glutamate receptors (mGluRs) represent a potential therapeutic target. Possible anticonvulsant action of AMN 082, an agonist of mGluR7 subtype, was studied in immature rats using pentylenetetrazol (PTZ)-induced seizures as a model. Five age groups of rats (7-, 12-, 18-, 25-day-old and adult animals) were pretreated with AMN 082 in doses of 0.5, 1, 2, and 5 mg/kg i.p. and 30 min lat...
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