The spectroscopy, electrochemistry, and electrogenerated chemiluminescence (ECL) of [(q)(qH)Li]x (qH=8-hydroxyquinolinato) and [(Meq)(MeqH)Li]x (MeQH=2-methyl-8-hydroxyquinolinato) have been investigated. In both acetonitrile and aqueous solutions, [(q)(qH)Li]x and [(Meq)(MeqH)Li]x have absorption maxima at 320 and 309 nm, respectively. When excited at these wavelengths, the complexes emit arou...

A lithium-boron complex, lithium tetra (2-methyl 8-hydroxy quinolinato) boron (LiBqm4), which emits greenish-blue light has been synthesized by the reaction of LiBH4 with 2-methyl 8-hydroxyquinoline in a molecular weight ratio of 1:4, and used for organic light emitting diodes (OLEDs) fabrication. The complex has been characterized by optical absorption, Fourier Transform Infrared (FTIR), photo...

Dysfunction of the ubiquitin-proteasome system (UPS) and accumulation of iron in substantia nigra (SN) are implicated in the pathogenesis of Parkinson's disease (PD). UPS dysfunction and iron misregulation may reinforce each other's contribution to the degeneration of dopamine (DA) neurons. In the present study, we use a new brain-permeable iron chelator, VK-28 [5-(4-(2-hydroxyethyl) piperazin-...

A novel 4-[(8-hydroxyquinolin-5-yl)methyl]aminobenzenesulfonamide (HQMABS) was synthesized by optimized reaction of 4-aminobenzenesulfonamide with 5-chloromethyl-8-hydroxyquinoline hydrochloride (CMHQ). Various oxinates of HQMABS were also prepared using Mn(II), Fe(II), Co(II), Ni(II), Cu(II), and Zn(II) metal salts. All compounds were analyzed by physicochemical, thermogravimetric and spectros...

Naturally occurring quinolone and quinolone-like compounds, such as quinine, 2-hydroxyquinoline, 4-hydroxyquinoline, and 2-heptyl-3-hydroxy-4(1H)-quinolone, increased expression of qnrS1 in Escherichia coli 2.3- to 11.2-fold, similar to the synthetic quinolone ciprofloxacin. In contrast, chromosomal qnrVS1 of Vibrio splendidus was not induced by these compounds. Molecules associated with quorum...