BACKGROUND Placental insufficiency is a major cause of antepartum stillbirth and fetal growth restriction (FGR). In affected pregnancies, delivery is expedited when the risks of ongoing pregnancy outweigh those of prematurity. Current tests are unable to assess placental function and determine optimal timing for delivery. An accurate, non-invasive test that clearly defines the failing placenta ...

Magnetic resonance spectroscopy (MRS) noninvasively provides information on the concentration of some cerebral metabolites in vivo. Among those measurable by proton magnetic resonance spectroscopy (1H-MRS), N-acetyl-aspartate (NAA) is decreased, and myo-inositol (ml) and choline (Cho) levels are increased in patients with Alzheimer's disease (AD). Donepezil, an acetylcholinesteraze inhibitor, h...

OBJECTIVE Neuro-Behcet's disease (NBD) is one of the most serious complications of Behcet's disease (BD). Proton magnetic resonance spectroscopy (1H MRS) has been proved to be useful in detecting neuro-metabolic abnormalities in various diseases affecting the brain. In this study, we attempted to characterize the magnetic resonance imaging (MRI) findings in Korean patients with NBD and then exa...

The purpose of this study was to evaluate the effect of verapamil administration on Human Fetuses in High Risk Pregnancies (FHRP) by Proton Magnetic Resonance Spectroscopy (HMRS) after Lactate identification. Two HMRS studies were performed on a 1.5 Tesla system using the body RF coil: the first one was done between 30-31 weeks of gestation and the second between 34-35 weeks after verapamil adm...

OBJECTIVES To assess the diagnostic value of multiparametric-MRI (MPMRI) with hypoxia imaging as a functional marker for characterizing and detecting vaginal vault/local recurrence following primary surgery for cervical cancer. METHODS With institutional review board approval and written informed consent 30 women (median age: 45 years) from October 2009 to March 2010 with previous operated ca...