polycystic ovary syndrome (pcos) is a common endocrine / metabolic disorder in women of reproductive age .abdominal adiposity and obesity are frequently present in pcos. it now appears that, obesity is associated with a low-grade inflammation of white adipose tissue. adipokines play a significant role in the pathogenesis of a low-grade inflammation associated with obesity. among variety of adip...

pemphigus vulgaris (pv) is often complicated by osteoporosis. although corticosteroid therapy undoubtedly plays a causative role, inflammation associated with pv may also contribute to osteoporosis. this study was designed to determine the prevalence of osteoporosis in patients with pv before corticosteroid therapy and to compare these findings with those reported previously in healthy voluntee...

Background: Maximal respiratory pressures are suitable for non –invasive evaluation of respiratory muscle function A variety of methods for subject selection and test procedures have been used for the determination of normal values and reference equations for maximal respiratory pressure (MRP). Materials and Methods: we analyzed a well-defined, healthy subgroup of 224 men and 211 women with a w...

Background: Oral lichen planus is a chronic inflammatory disease with a poorly understood etiology. The role of angiogenesis in the development of different chronic inflammatory diseases is of great concern. Vascular endothelial growth factor (VEGF) is an important regulator of angiogenesis. We aimed to evaluate the serum level of VEGF in patients with oral lichen planus compared with normal in...

UNLABELLED Aim. The aim of this study was to investigate the influence of age, gender, obesity and scaling on glomerular filtration rate (GFR) and extracellular fluid volume (ECV) in healthy subjects. METHODS This is a retrospective multi-centre study of 1878 healthy prospective kidney transplant donors (819 men) from 15 centres. Age and body mass index (BMI) were not significantly different ...

Coagulase negative Staphylococcus has long been considered of little significance as a urinary tract infection. The role of novobiocin resistant coagulase-negative Staphylococcus saprophyticus in infection of the urinary tract of women of childbearing age (14-40 years; mean age = 27 years; outpatients) was investigated. Three hundred female patients between the age bracket of 14 and 40 years (m...

BACKGROUND different studies have demonstrated the correlation between anorectal manometry and endoanal ultrasonography data in patients with fecal incontinence, but there is no almost interest describing the same in healthy subjects according to age. AIMS to study the possible correlation between anorectal manometry and endoanal ultrasonography data in a homogeneous group of healthy women, a...

The aim of this study was to determine whether the healthy worker effect and its component parts operate similarly for women and men. A cohort of workers from 14 synthetic vitreous fiber factories in seven countries, employed for at least 1 year between 1933 and 1977 and followed up to the early 1990s, included 375 deaths and 53,608 person-years among females and 2,568 deaths and 210,073 person...

1. Biopsy specimens of muscle obtained after an overnight rest from 14 men and eight women, apparently healthy subjects (age range 52-79 years), were analysed for pyruvate, lactate and energy-rich phosphagens. 2. Values for metabolites showed no sex differences. Compared with previous findings in men and women about 40 years younger, the intramuscular concentrations of both total adenine nucleo...

Adverse changes in coagulation and fibrinolytic factors are thought to contribute to the increased risk of cardiovascular disease and atherothrombosis with age. We tested the hypothesis that such age-related changes in specific coagulation and fibrinolytic factors are absent in physically active women. Resting levels of plasma fibrinogen, tissue-type plasminogen activator (t-PA) antigen and act...