The simultaneous effects of the cytochrome P450 inhibitor 1-aminobenzotriazole (ABT) on inhibition of in vivo metabolism and gastric emptying were evaluated with the test compound 7-(3,5-dimethyl1H-1,2,4-triazol-1-yl)-3-(4-methoxy-2-methylphenyl)-2,6-dimethylpyrazolo[5,1-b]oxazole(NVS-CRF38), a novel corticotropin releasing factor receptor 1 (CRF1) antagonist with low water solubility, and the ...

Dendritic spines appear and disappear in an experience-dependent manner. Although some new spines have been shown to contain synapses, little is known about the relationship between spine addition and synapse formation, the relative time course of these events, or whether they are coupled to de novo growth of axonal boutons. We imaged dendrites in barrel cortex of adult mice over 1 month, track...

R.S. Thorne Cavendish Laboratory, University of Cambridge, UK Abstract I discuss the issue of uncertainties in parton distributions and in the physical quantities which are determined in terms of them. While there has been significant progress on the uncertainties associated with errors on experimental data, there are still outstanding questions. Also, I demonstrate that in many circumstances t...

A better understanding of the controls on algae and dissolved O2 in agricultural streams of Illinois is needed to aid in development of nutrient standards. We investigated the relationships between dissolved nutrients, algal abundance, and dissolved O2 in five streams in east-central Illinois from March through November 2004. The streams drained watersheds from 25 to 777 km that were dominated ...

Ádám Kun, Gergely Boza, and István Scheuring Department of Plant Taxonomy and Ecology, Eötvös University, Pázmány Péter sétány 1/C, H-1117 Budapest, Hungary, Collegium Budapest, Institute for Advanced Study, Szentháromság u. 2, H-1014 Budapest, Hungary, and Department of Plant Taxonomy and Ecology, Research Group of Ecology and Theoretical Biology, Eötvös University, Hungarian Academy of Scienc...

Elisabeth A. Cox-Paulson,1 Elise Walck-Shannon,2 Allison M. Lynch,3 Sawako Yamashiro,4,5 Ronen Zaidel-Bar,3,6 Celeste C. Eno,2 Shoichiro Ono,4 and Jeff Hardin2,3,* 1Department of Biology, State University of New York at Geneseo, 353 Integrated Science Center, 1 College Circle, Geneseo, NY 14454, USA 2Program in Genetics, University of Wisconsin–Madison, 1117 W. Johnson Street, Madison, WI 53706...