Changes in activity-dependent calcium flux through voltage-gated calcium channels (CaVs) drive two self-regulatory calciumdependent feedback processes that require interaction between Ca2+/calmodulin (Ca2+/CaM) and a CaV channel consensus isoleucine-glutamine (IQ) motif: calcium-dependent inactivation (CDI) and calcium-dependent facilitation (CDF). Here, we report the high-resolution structure ...

The Health Insurance Flexibility and Accountability (HIFA) demonstration initiative is a significant milestone in the evolution of the states’ ability to use section 1115 of the Social Security Act. Section 1115 gives the Secretary of the U.S. Department of Health and Human Services (HHS) the discretion to let states modify Medicaid and the State Children’s Health Insurance Program (SCHIP) by w...

This issue brief explores the history and context of the Section 1115 Medicaid waiver authority, discusses the Health Insurance Flexibility and Accountability (HIFA) initiative under way in the Bush administration, and considers some of the potential impacts that HIFA could have on state budgets and access to health care for low-income families. Finally, it considers the future of Section 1115 ...

Section 1115 of the Social Security Act permits the Secretary of the Department of Health and Human Services (DHHS) to waive certain portions of the federal Medicaid Act for a fiveyear demonstration project, if the demonstration is budget neutral to the federal government. Once the budget neutrality test is met, the Secretary, through the Health Care Financing Administration (HCFA), can grant a...

1 Department of Physiology, Faculty of Basic Medical Sciences, College of Medical Sciences, University of Calabar, P.M.B. 1115 Calabar, Cross River State, Nigeria. 2 Department of Physiology, Faculty of Basic Medical Sciences, College of Health Sciences, University of Uyo, Uyo, Akwa Ibom State, Nigeria. 3 Department of Biochemistry, Faculty of Basic Medical Sciences, College of Medical Sciences...

*School of Natural Resources and Environment, University of Michigan, 430 E. University Avenue, Ann Arbor, Michigan 48109-1115, U.S.A. Corresponding author present address: Institute for Fisheries Research, University of Michigan, 212 Museums Annex Bldg., Ann Arbor, Michigan 48109-1084, U.S.A. [email protected] School of Natural Resources and Environment, University of Michigan, 430 E. Universi...

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This article discusses how States have taken advantage of the flexibility afforded under section 1115 research and demonstration authority. It describes how States have used Section 1115 authority to develop innovations in outreach and enrollment, eligibility requirements, access, benefits, quality assurance, payment, safety net providers, and special needs populations. It concludes by discussi...

With the demise of health care reform at the national level, much of the attention has shifted to state-level efforts. Recently, several states have begun looking to the Medicaid program as a way to solve their health care problems. A principal way in which states are implementing health care reform is through the Section 1115 research and demonstration Medicaid waiver program. The 1115 waiver ...