Phytophthora sojae Kaufmann and Gerdemann, which causes Phytophthora root rot, is a widespread pathogen that limits soybean production worldwide. Development of Phytophthora resistant cultivars carrying Phytophthora resistance Rps genes is a cost-effective approach in controlling this disease. For this mapping study of a novel Rps gene, 290 recombinant inbred lines (RILs) (F7 families) were dev...

background: inherited thrombophilic gene polymorphisms have been related to the pathogenesis of venous thromboembolism and its outcomes. considering the scarcity of data on the frequency of the thrombophilic gene polymorphisms in iranian populations, the aim of this study was to assess such polymorphisms in healthy individuals. materials and methods: this cross-sectional study was performed on ...

Angiopoietin-like proteins (ANGPTL) are a family of several proteins, which ANGPTL3, 4 and 8 involved in lipid metabolism. These discovered relatively recently, regulate the availability triglycerides for heart, skeletal muscles white brown adipose tissue depending on nutritional status body, thus contributing to maintenance energy homeostasis. gene mutations associated with significant reducti...

Clinical respiratory illness was compared in five homozygous chicken lines, originating from homozygous B2, B8, B12 and B19, and heterozygous B2/B12 birds after infection with either of two strains of the infectious bronchitis virus (IBV). All chickens used in these studies originated from White Leghorn and Ancona linages. IBV Gray strain infection of MHC homozygous B12 and B19 haplotype chicks...

A wild house mouse (Mus domesticus) population originally trapped near Reading, Berkshire, United Kingdom, and maintained as a colony in the laboratory, was subjected to the discriminating feeding period of the warfarin resistance test, as used by Wallace and MacSwiney (1976) and derived from the work of Rowe and Redfern (1964). Eighty percent of this heterogeneous population survived the resis...

Myrtle rust (MR) caused by Austropuccinia psidii is one of the most important diseases affecting eucalypt (Eucalyptus) plantations in Brazil. Over years, selection and planting MR-resistant clones has been primary strategy for MR management. In May 2013, young trees GG100 hybrid (E. grandis × E. urophylla) clone—widely planted Brazil previously classified as resistant to MR—were infected A. Min...

Selectively outbred Dahl salt-sensitive (DS) and salt-resistant (DR) rats were compared with the inbred Dahl salt-sensitive (SS/Jr) and salt-resistant (SR/Jr) rats developed from the original Brookhaven stocks by J.P. Rapp. The animals were evaluated for genotype at the renin locus. The inbred strains are uniformly homozygous for their respective alleles, s in SS/Jr and r in SR/Jr. DR rats were...

seedlessness is the most important trait in table grape and raisin industry which has attracted breeders from long ago. breeding grapes by traditional methods result in low number of seedless progenies and their selection requires long time. therefore, marker-assisted selection (mas) can overcome the selection difficulty and would decrease high cost of progeny maintenance for several years. in ...

BACKGROUND Glioblastoma multiforme (GBM) displays multiple amplicons and homozygous deletions that involve relevant pathogenic genes and other genes whose role remains unknown. METHODOLOGY Single-nucleotide polymorphism (SNP)-arrays were used to determine the frequency of recurrent amplicons and homozygous deletions in GBM (n = 46), and to evaluate the impact of copy number alterations (CNA) ...

This study aimed to evaluate genotype-phenotype correlations of Parkinson’s disease (PD) patients with phospholipase A2 group V (PLA2G6) variants. We analyzed the DNA 798 PD, including 78 PD reported previously, and 336 in-house controls. screened exons exon-intron boundaries PLA2G6 using Ion Torrent system Sanger method. identified 21 18 rare variants, such that 1, 9, 11 were homozygous, heter...