The field of the extended TeV source HESS J1804−216 was serendipitously observed with the Chandra ACIS detector on 2005 May 4. The data reveal several X-ray sources within the bright part of HESS J1804−216. The brightest of these objects, CXOU J180432.4−214009, which has been also detected with Swift (2005 November 3) and Suzaku (2006 April 6), is consistent with being a point-like source, with...

Alzheimer’s disease is one of the most common causes of death worldwide, with poor treatment options. A tissue landmark of Alzheimer’s disease is accumulation of the anomalous protein amyloid-b in specific brain areas. Whether inflammation is an effect of amyloid-b on the Alzheimer’s disease brain, or rather it represents a cause for formation of amyloid plaques and intracellular tangles remain...

Tradeoffs centrally mediate the expression of human adaptations. We propose that tradeoffs also influence the prevalence and forms of human maladaptation manifest in disease. By this logic, increased risk for one set of diseases commonly engenders decreased risk for another, diametric, set of diseases. We describe evidence for such diametric sets of diseases from epidemiological, genetic and mo...

Widespread premature termination codon mutations (PTCs) were recently observed in human and fly populations. We took advantage of the population resequencing data in the Drosophila Genetic Reference Panel to investigate how the expression profile and the evolutionary age of genes shaped the allele frequency distribution of PTCs. After generating a high-quality data set of PTCs, we clustered gen...

Tall fescue (Festuca arundinacea Schreb.) is an important forage resource for beef (Bos taurus L.) production in the North–South transition zone. Recently, the cultivar ‘Jesup’ was released to provide improved stand survival when infected with a novel (nontoxic) endophyte marketed as MaxQ (Pennington Seed, Madison, GA), and warrants evaluation as a source of winter hay for beef cattle. Intake a...

BACKGROUND AND PURPOSE Stent-assisted coiling has expanded the treatment of intracranial aneurysms, but the rates of procedure-related neurological complications and the incidence of angiographic aneurysm recurrence of this novel treatment are not yet well known. We present our experience with stent-assisted coiling with special emphasis on procedure-related neurological complications and incid...

Background and Purpose—Stent-assisted coiling has expanded the treatment of intracranial aneurysms, but the rates of procedure-related neurological complications and the incidence of angiographic aneurysm recurrence of this novel treatment are not yet well known. We present our experience with stent-assisted coiling with special emphasis on procedure-related neurological complications and incid...