In present study, growth, arsenic accumulation, and antioxidant responses in root of Isatis cappadocica were investigated in response to application of arsenate and phosphate. Reduction in root dry weights was significant with 1200 µM arsenate and 5 µM phosphate treatments. Phosphate had a steady effect on root dry weight improvement, especially in high arsenate treatments ≥ 200 μM. As concentr...

PURPOSE Heme oxygenase (HO)-1 immunoreactivity (IR) was examined in normal untreated retina and in retinal explants after in vitro treatment with stress agents. METHODS Enucleated eyes from young adult C3H mice were immediately fixed and cryosectioned and the retina sections processed for immunocytochemistry with antibodies against HO-1 and glial fibrillary acidic protein (GFAP). From other e...

We have performed two-stage transformation assay using BALB/c 3T3 cells to determine initiating and promoting activities of disodium arsenate, sodium arsenite, monomethylarsonic acid (MMAA) and dimethylarsinic acid (DMAA). Treatment with these arsenic compounds at the initiating stage induced significant numbers of transformed foci when cells were post-treated with 12-O-tetradecanoylphorbol-13-...

Sodium arsenate induces developmental malformations in a variety of experimental animals. In the golden hamster, the intravenous (or intraperitoneal) administration of 20 mg/kg of sodium arsenate during day 8 to 9 of gestation induces a rather specific spectrum of congenital malformations. This period corresponds to the period of very rapid differentiation and major organogenesis in this animal...

Arsenate (As (V)) is the dominant form of the toxic metalloid arsenic (As). Microorganisms have consequently developed mechanisms to detoxify and tolerate this kind of compounds. In the present work, we have explored the arsenate sensing and signaling mechanisms in the pathogenic fungus Candida albicans. Although mutants impaired in the Hog1 or Mkc1-mediated pathways did not show significant se...

27 In the present study, the effect of phosphate ion and iron hydroxides (Fe-plaques) on the 28 selective uptake of arsenic species by water fern (Salvinia natans L.) was investigated. The 29 plants were grown for 5 days in aqueous Murashige and Skoog (MS) culture media modified in 30 arsenic and phosphate concentrations. Arsenic accumulations in Salvinia natans L. increased 31 with the increas...

1. The methods employed in these and preceding (25-27) studies were shown to allow analysis of true cellular sodium and potassium concentrations. 2. The rate of reaccumulation of potassium by potassium-deficient cells is independent of the presence or absence of sodium in the external medium. 3. Phenylurethane (10(-3)M), a photosynthetic and metabolic inhibitor, causes a marked progressive loss...

Microbial arsenate resistance is known to be conferred by specialized oxidoreductase enzymes termed arsenate reductases. We carried out a genetic selection on media supplemented with sodium arsenate for multicopy genes that can confer growth to E. coli mutant cells lacking the gene for arsenate reductase (E. coli ΔarsC). We found that overexpression of glutathione S-transferase B (GstB) complem...

esca of grapevine is a serious and injurious disease in grape-growing all over the world, for which no effective control exists. the presented research ,in two separate experiments ,thirteen fungicides (benomyl, thiophanate-methyl thiram, mancozeb, fosetyl-al, metalaxyl mancozeb, caboxin thiram, ortiva, topas, penconazole , tebuconazole ,propiconazole, sodium arsenate, agri-fos ) were evaluated...