نتایج جستجو برای: ژن nd1

تعداد نتایج: 16327  

2012
Dong Tu Nguyen Tuan Cuong Ngo Huy Hoang Tran Thanh Huong Le Hoai Thu Nguyen Binh Minh Nguyen Nhu Duong Tran Tetsu Yamashiro Masahiko Ehara

During the cholera survey in Namdinh province (northern Vietnam) in July, 2010, one strain of Vibrio cholerae O139 was isolated from 7 environmental water samples positive for ctxA, toxR,VCO139 genes and named as V. cholerae O139, ND1 strain. This strain was lysogenic harbouring a genome similar to the filamentous phage fs1. The replicative form DNA of this phage (named as ND1-fs1, 6856 bp) was...

Journal: :Human molecular genetics 2012
Olga Zurita Rendón Eric A Shoubridge

Complex I (CI, NADH ubiquinone oxidoreductase), the largest complex of the respiratory chain, is composed of 45 structural subunits, 7 of which are encoded in mtDNA. At least 10 factors necessary for holoenzyme assembly have been identified; however, the specific roles of most of them are not well understood. We investigated the role of NDUFAF3, NDUFAF4, C8orf38 and C20orf7, four early assembly...

2013
Nikhil Jain Neha Vithani Abu Rafay Balaji Prakash

A role for HflX in 50S-biogenesis was suggested based on its similarity to other GTPases involved in this process. It possesses a G-domain, flanked by uncharacterized N- and C-terminal domains. Intriguingly, Escherichia coli HflX was shown to hydrolyze both GTP and adenosine triphosphate (ATP), and it was unclear whether G-domain alone would explain ATP hydrolysis too. Here, based on structural...

2008
Yu Fang-Bo Guan Li-Bo Zhou Shan

This paper reports the isolation and characterization of a new o-nitrobenzaldehyde (ONBA)-degrading bacterium, Alcaligenes sp. ND1. ND1 degraded almost all ONBA (100 mg L(-1)) in M9 medium within 36 hours. The key enzyme(s) involved in the initial biodegradation was a constitutively intracellular enzyme(s). This bacterium has great potential utility for bioremediation.

2016
Hakushi Kim Tomoyoshi Komiyama Chie Inomoto Hiroshi Kamiguchi Hiroshi Kajiwara Hiroyuki Kobayashi Naoya Nakamura Toshiro Terachi

We analyzed mutations in the mitochondrial ND1 gene to determine their association with clinicopathological parameters and postoperative recurrence of renal cell carcinoma (RCC) in Japanese patients. Among 62 RCC cases for which tumor pathology was confirmed by histopathology, ND1 sequencing revealed the presence of 30 mutation sites in 19 cases. Most mutations were heteroplasmic, with 16 of 19...

2015
Shabnam TADAYON Hassan SHARIFIYAZDI Mohammad MOAZENI Mohammad Reza DIVAR

BACKGROUND Fasciola hepatica and F. gigantica are the causative agents of fasciolosis in domestic animals and humans. Based on the morphometric criteria, differential diagnosis between them is problematic. In addition, intermediate forms of Fasciola have been found in Iran, which makes the differentiation more difficult. The aim of the present study was to provide molecular evidence for the exi...

2006
S. C. Wang

Sintered NdFeB magnets are relatively complex multiphase systems containing Nd2Fe14B matrix and about 15% of other intermetallics such as Nd1+εFe4BB4, Nd-oxides (Nd-rich phase), etc. Boron rich Nd1+εFe4B4 B forms in irregularly distributed heavily faulted grains of roughly the same size as those of the Nd2Fe14B phase [1]. The Curie temperature of this phase is 13K and, therefore, it is not ferr...

Journal: :Human molecular genetics 2014
Luisa Iommarini Ivana Kurelac Mariantonietta Capristo Maria Antonietta Calvaruso Valentina Giorgio Christian Bergamini Anna Ghelli Patrizia Nanni Carla De Giovanni Valerio Carelli Romana Fato Pier Luigi Lollini Michela Rugolo Giuseppe Gasparre Anna Maria Porcelli

Mitochondrial DNA mutations are currently investigated as modifying factors impinging on tumor growth and aggressiveness, having been found in virtually all cancer types and most commonly affecting genes encoding mitochondrial complex I (CI) subunits. However, it is still unclear whether they exert a pro- or anti-tumorigenic effect. We here analyzed the impact of three homoplasmic mtDNA mutatio...

2017
Mi-Hee Jun Hyun-Hee Ryu Yong-Woo Jun Tongtong Liu Yan Li Chae-Seok Lim Yong-Seok Lee Bong-Kiun Kaang Deok-Jin Jang Jin-A Lee

Mutations in fused in sarcoma (FUS), a DNA/RNA binding protein, are associated with familial amyotrophic lateral sclerosis (ALS). However, little is known about how ALS-causing mutations alter protein-protein and protein-RNA complexes and contribute to neurodegeneration. In this study, we identified protein arginine methyltransferase 1 (PRMT1) as a protein that more avidly associates with ALS-l...

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