The MEDA pole comprises physicians conducting research in the three acute medicine units of the UCL Cliniques Universitaires Saint-Luc and CHU UCL Namur site Mont-Godinne: anesthesiology, intensive care, and emergency medicine. Our primary research work is devoted to clinical research, from local original studies to international multicenter studies, either academic or industry-sponsored. The M...

Request oriented sensor networks have stricter requirements than conventional event-driven or periodic report models. Therefore, in this paper we propose a minimum energy data aggregation (MEDA), which meets the requirements for request oriented sensor networks by exploiting a low power real-time scheduler, ondemand time synchronization, variable response frame structure, and adaptive retransmi...

Under mild conditions, it can be induced from the Karush-Kuhn-Tucker condition that the Pareto set, in the decision space, of a continuous multiobjective optimization problem is (m− 1)-D piecewise continuous, where m is the number of objectives. Based on this regularity property, we propose a Regularity Model based Multiobjective Estimation of Distribution Algorithm (RM-MEDA) for continuous mul...

Under mild conditions, it can be induced from the Karush–Kuhn–Tucker condition that the Pareto set, in the decision space, of a continuous Multiobjective Optimization Problems(MOPs) is a piecewise continuous ( 1) m D   manifold(where m is the number of objectives). One hand, the traditional Multiobjective Optimization Algorithms(EMOAs) cannot utilize this regularity property; on the other han...

The Meda inequality for rearrangements of the convolution operator on the Heisenberg group Hn is proved. By using the Meda inequality, an O’Neil-type inequality for the convolution is obtained. As applications of these results, some sufficient and necessary conditions for the boundedness of the fractional maximal operator MΩ,α and fractional integral operator IΩ,α with rough kernels in the spac...

The directed generation of pure astrocyte cultures from pluripotent stem cells has proven difficult. Generation of defined pluripotent-stem-cell derived astrocytes would allow new approaches to the investigation of plasticity and heterogeneity of astrocytes. We here describe a two-step differentiation scheme resulting in the generation of murine embryonic stem cell (mESC) derived astrocytes (ME...

3,4-(±)-Methylenedioxymethamphetamine (MDMA) and 3,4-(±)-methylenedioxyamphetamine (MDA), a primary metabolite of MDMA, are phenylethylamine derivatives that cause serotonergic neurotoxicity. Although several phenylethylamine derivatives activate microglia, little is known about the effects of MDMA on glial cells, and evidence of MDMA-induced microglial activation remains ambiguous. We initiall...

Let dγ(x) ≡ πe 2 dx for all x ∈ R be the Gauss measure on R. In this paper, the authors establish the characterizations of the space BMO(γ) of Mauceri and Meda via commutators of either local fractional integral operators or local fractional maximal operators. To this end, the authors first prove that such a local fractional integral operator of order β is bounded from L(γ) to L(γ), or from the...