نتایج جستجو برای: ژن coxi
تعداد نتایج: 15874 فیلتر نتایج به سال:
DNA میتوکندریایی یکی از گستردهترین نشانگرهای مولکولی برای مطالعات فیلوژنتیک در حیوانات به علت ساختار ژنوم ساده آن است.این مطالعه ویژگیهای ژنتیکی بزهای بومی را با استفاده از تجزیه و تحلیل توالی ( DNA Cytocrome oxidase I (COXI برای شناسایی و تمایز بین سه نژاد (نجدی، عدنی و مرخز) ایران بررسی میکند. اس...
LRPPRC (leucine-rich pentatricopeptide repeat-containing) has been shown to be essential for the maturation of COX (cytochrome c oxidase), possibly by stabilizing RNA transcripts of COXI, COXII and COXIII genes encoded in mtDNA (mitochondrial DNA). We established a mouse 'gene-trap' model using ES cells (embryonic stem cells) in which the C-terminus of LRPPRC has been replaced with a β-geo cons...
The aim of the present study was to test the hypothesis that peroxisome proliferator activated receptor-gamma coactivator (PGC) 1alpha is required for exercise-induced adaptive gene responses in skeletal muscle. Whole body PGC-1alpha knockout (KO) and littermate wild-type (WT) mice performed a single treadmill-running exercise bout. Soleus and white gastrocnemius (WG) were obtained immediately,...
Protein synthesis in mitochondria is initiated by formylmethionyl-tRNA(Met) (fMet-tRNA(Met)), which requires the activity of the enzyme MTFMT to formylate the methionyl group. We investigated the molecular consequences of mutations in MTFMT in patients with Leigh syndrome or cardiomyopathy. All patients studied were compound heterozygotes. Levels of MTFMT in patient fibroblasts were almost unde...
BACKGROUND Mitochondrial biogenesis program in heart appears to exhibit adaptive remodeling following biomechanical and oxidative stress. The adaptive mechanisms that protect myocardium metabolism during hypoxia are coordinated in part by nitric oxide (NO). OBJECTIVE To observe mitochondrial biogenesis and nitric oxide synthase (NOS) expression in hearts of congenital heart disease with cyano...
Philosamia ricini, the Indian eri silkworm, contributes significantly to the production of commercial silk and is widely distributed in the Brahmaputra valley of the North-Eastern India. Strains of P. ricini show wide variation in their phenotypic traits and are commercially exploited in these places because of their high silk yield potential. In this study, we have analyzed the partial mitocho...
The recognition and translation of mammalian mitochondrial mRNAs are poorly understood. To gain further insights into these processes in vivo, we characterized mice with a missense mutation that causes loss of the translational activator of cytochrome oxidase subunit I (TACO1). We report that TACO1 is not required for embryonic survival, although the mutant mice have substantially reduced COXI ...
The complete mitochondrial genome of Aluterus monoceros (A. monoceros) has been sequenced. The mitochondrial genome of A. monoceros is 16,429 bp in length, consisting of 22 tRNA genes, 2 rRNA genes, 13 protein-coding genes and a D-loop region (Gen Bank accession number KP637022). The base A + T of the mitochondrial genome is 63.25%, including 33.16% of A, 30.09% of T and 20.74% of C. Twelve pro...
The role of domain 5 (d5) from the self-splicing group II intron 5 gamma of the COXI gene of yeast mitochondrial DNA in branching and 3' splice site utilization has been studied using a substrate transcript lacking d5 (delta d5 RNA). This RNA is completely unreactive in vitro, but releases 5' exon by hydrolysis under various reaction conditions when d5 RNA is added in trans. Under an extreme re...
رطیل ها یکی از ارکان مهم، فون جانواران محیط زیست خشک و نیمه خشک محسوب می شوند.راسته رطیل ها ازنظرتعدادخانواده ها، جنس ها و گونه هاششمینراستهمتنوععنکبوتیانمی باشد کهدرسرتاسرجهانبهجزء استرالیا،ماداگاسکار،قطب جنوب و جزایراقیانوس آرام پراکنده شده اند. مطالعاتاندک انجام شده بر روی این آرایه سبب شده که مقدار زیادی از آرایه شناسی، تبارشناختی، بوم-شناختی، و فیزیولوژی این آرایه به طور ناشناخته باقی بمان...
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