PURPOSE The aim of this study was to determine the possible association of rs1048661 and rs3825942 single nucleotide polymorphisms (SNPs) in the lysyl oxidase-like 1 (LOXL1) gene of cataract patients from southwestern Greece with pseudoexfoliation (PEX) syndrome. PATIENTS AND METHODS Ninety-three patients with PEX syndrome and 74 without PEX syndrome were recruited with the principal diagnosi...

Excess energy was measured with a Seebeck envelope calorimeter in an electrolytic system containing a 2 mm diameter Pd tube cathode. After about 50 hours of electrolysis, many power pulses (Pex < ∼0.5 W) and bursts (Pex > ∼0.5 W) of excess power Pex were observed. The distribution of the number of power pulses N(Pex) with definite excess power Pex plotted on a logarithmic scale is expressed as ...

Angiogenesis, tumor cell proliferation, and migration are the hallmarks of solid tumors, such as gliomas. This study demonstrates that a fragment derived from the autocatalytic digestion of matrix metalloproteinase (MMP)-2, called PEX, acts simultaneously as an inhibitor of glioma angiogenesis, cell proliferation, and migration. PEX is detected in the cultured medium of various human glioma, en...

BACKGROUND Pulmonary exacerbations (PEx) are critical events in cystic fibrosis (CF), responsible for reduced quality of life and permanent loss of lung function. Approximately 1/4 of PEx are associated with failure to recover lung function and/or resolve symptoms. Developing tools to optimize PEx treatment is of paramount importance. METHODS We retrospectively audited all adults infected wit...

BACKGROUND Plasma exchange (PEX) treatment for patients with thrombotic thrombocytopenic purpura-hemolytic uremic syndrome (TTP-HUS) has risk for major complications. STUDY DESIGN AND METHODS Data for PEX-related complications have been prospectively collected on all patients enrolled in the Oklahoma TTP-HUS Registry, 1996 to 2011. PEX-related complications have been defined as major or minor...

Excess energy was measured with a Seebeck envelope calorimeter in an electrolytic system containing a 2 mm diameter Pd tube cathode. After about 50 hours of electrolysis, many power pulses (Pex < ∼0.5 W) and bursts (Pex > ∼0.5 W) of excess power Pex were observed. The distribution of the number of power pulses N(Pex) with definite excess power Pex plotted on a logarithmic scale is expressed as ...

PURPOSE Pseudoexfoliation (PEX) syndrome is a generalized elastic microfibrillopathy characterized by fibrillar deposits in intra- and extraocular tissues. Genetic and nongenetic factors are known to be involved in its etiopathogenesis. This study was focused on six functional candidate genes involved in PEX material deposition and the analysis of their potential association with PEX syndrome a...

Pex automatically produces a small test suite with high code coverage for a .NET program. To this end, Pex performs a systematic program analysis (using dynamic symbolic execution, similar to pathbounded model-checking) to determine test inputs for Parameterized Unit Tests. Pex learns the program behavior by monitoring execution traces. Pex uses a constraint solver to produce new test inputs wh...

The time measurement system of the unicellular cyanobacterium Synechococcus elongatus PCC 7942 is analogous to the circadian clock of eukaryotic cells. Circadian clock-related genes have been identified in this strain. The clock-related gene pex is thought to maintain the normal clock period because constitutive transcription or deficiency of this gene causes respectively longer (approximately ...

The distribution system is the primary cause of taste and odor complaints in drinking water. This research examined the ability of small diameter pipes used in home plumbing to affect drinking water quality. The properties of the materials were investigated in the absence of disinfectant and the presence of either chlorine or chloramines. A panel was trained in flavor profile analysis (FPA) acc...