Macrophomina phaseolina (Tassi) Goid is a soil-borne fungal pathogen that causes root rot disease in more than 500 plant species but no registered fungicide is available for its control. The present study was carried out to investigate the antifungal activity of aqueous leaf extracts of Azadirachta indica A. Juss., Melia azedarach L. and Toona ciliata Roxb. (Meliaceae) against M. phaseolina. Aq...

Subcutaneous treatment of 50% EtOH extract of neem bark (Azadirachta indica A. juss) to male rats at the dose of 10 mg for 30 days caused arrest of spermatogenesis. The diameter of serminiferous tubule, Leydig cell nucleus and epithelial heights of epididymides were significantly reduced (p≤0.001). Sperm motility and density were significantly reduced. Reduced testicular and accessory organ pro...

The antifeedant and anthelmintic activities of crude extracts of the shells of Anacardium occidentale were studied by comparing it's activity with the activity of Azadirachta indica A Juss (Kernel), a commercial standard. The test extracts of A. occidentale in petroleum ether, dichloromethane: methanol showed better activities compared to A. Indica. To Study the anthelmintic activity, the addit...

Locusta migratoria, Azadirachta indica, Ecdysteroids, Azadirachtin, Ovary The sterilizing effect of azadirachtin, an insect growth regulator from the neem tree, Azadirachta indica A. Juss, was tested with mature females of Locusta migratoria. After a single injection of 10 |ig into females between 2 and 13 days after emergence, about 60% died during the following four days and all lost weight i...

In the present study, the efficacy of 6 different species of medicinal plants belonging to 5 different families against Biomphalaria alexandrina snails and Schistosoma mansoni stages were examined. During screening test of water suspension and methanol extract, results revealed that Oreopanax reticulatum (Family: Araliaceae) had the strongest molluscicidal activity against Biomphalaria alexandr...

Nimbidin the major bitter principle from oil of seeds of Azadirachta indica A. Juss was investigated for various pharmacological actions in a number animal models. On central nervous system it exhibited moderate sedative effect it did not show any significant cardiovascular effects in experimental animals. Autonomic pharmacological studies (in-vitro) revealed pronounced anticholinergic antihist...

Organic extracts of the leaves of Azadirachta indica A. Juss. yielded ten antitrypanosomal terpenoids. Three of these (1-3), are novel and are derivatives of nimbolide and nimbin. They were extracted from chloroform fraction of methanol extract. These compounds were found to exhibit strong antitrypanosomal activities against Trypanosoma brucei rhodesiense with MIC values ranging of 6.9, 15.6 an...

The in vitro toxicity of neem seed oil (Azadirachta indica A. Juss, family: Meliaceae, Dogon yaro in Hausa language in Nigeria) was tested against the larvae of a one-host tick, Boophilus decoloratus (family: Ixodidae or hard tick, commonly known as blue tick) parasitic mainly to cattle generally found in savannas of tropical equatorial Africa. The 20, 40, 60, 80 and 100% concentrations of neem...