Intraperitoneal (IP) injection of bupropion (3,6,
amine (4,16 mg kg•') induced dose-dependent climbing in mice. The climbing
response induced by both drugs were decreased in animals pretreated either with
the 0-1 antagonist SCH 233<)0 or the 0-2 antagonist sulpiride. The α-adrenoceptor
blocker phenoxybenzamine decreased the climbing induced by both bupropion
and amphetamine, but the β-ad...