نتایج جستجو برای: نمایه rdi

تعداد نتایج: 6545  

Journal: :Antimicrobial agents and chemotherapy 2009
Shilpi Sharma Diane Thomas John Marlett Marianne Manchester John A T Young

A soluble receptor decoy inhibitor (RDI), comprised of the extracellular I domain of ANTXR2, is a candidate anthrax therapeutic. Here we show that RDI can effectively neutralize altered forms of the protective antigen toxin subunit that are resistant to 14B7 monoclonal antibody neutralization. These data highlight the potential of RDI to act as an adjunct to existing antibody-based therapies an...

2015
Jana Orsavova Ladislava Misurcova Jarmila Vavra Ambrozova Robert Vicha Jiri Mlcek Cenk Suphioglu

Characterizations of fatty acids composition in % of total methylester of fatty acids (FAMEs) of fourteen vegetable oils--safflower, grape, silybum marianum, hemp, sunflower, wheat germ, pumpkin seed, sesame, rice bran, almond, rapeseed, peanut, olive, and coconut oil--were obtained by using gas chromatography (GC). Saturated (SFA), monounsaturated (MUFA) and polyunsaturated fatty acids (PUFA),...

2016
Tamaki Amano Motomi Toichi

Eye movement desensitisation and reprocessing (EMDR) is a standard method for treating post-traumatic stress disorder. EMDR treatment consists of desensitisation and resource development and installation (RDI) stages. Both protocols provide a positive alternating bilateral stimulation (BLS). The effect of desensitisation with BLS has been elucidated. However, a role for BLS in RDI remains unkno...

Journal: :Oncology letters 2011
Tetsuya Komatsu Yukio Oizumi Etsuo Kunieda Yoshifumi Tamai Takeshi Akiba Asuka Kogawa

The aim of this study was to evaluate potential predictive factors in the treatment of limited-disease small cell lung cancer (LD-SCLC). A total of 33 patients with LD-SCLC who underwent definitive chemoradiotherapy at our institute between April 1996 and May 2007 were enrolled in our retrospective study. The relationship between a range of potential predictive factors and the initial response,...

Journal: :Oncology nursing forum 2012
Deborah A Griffin Barbara Penprase Justin F Klamerus

PURPOSE/OBJECTIVES To determine the amount of chemotherapy delivered compared to amount of chemotherapy scheduled by calculating relative dose intensity (RDI) and to identify factors associated with nonadherence of scheduled treatment regimens for patients with early-stage breast cancer (ESBC). DESIGN Retrospective, descriptive, correlational study. SETTING Two community hospital cancer cen...

2018
Akihiro Hirakawa Kan Yonemori Fumie Kinoshita Yumiko Kobayashi Hitomi S Okuma Asuka Kawachi Kenji Tamura Yasuhiro Fujiwara Larry Rubinstein Pamela Jo Harris Naoko Takebe

Phase 1 trials of molecularly targeted agents (MTA) often do not use toxicity data beyond the first cycle of treatment to determine a recommended phase 2 dose (RP2D). We investigated the potential utility of longitudinal relative dose intensity (RDI) that may be a better new way of determining a more accurate RP2D as a lower dose that is presumably more tolerable over the long term without comp...

Journal: :Archives of otolaryngology--head & neck surgery 2005
Kevin D Pereira Jeremy C Roebuck Lori Howell

OBJECTIVE To determine the association between body position and obstructive events during sleep as determined by polysomnography (PSG) in very young children (age, < or = 3 years) with obstructive sleep apnea syndrome. DESIGN Retrospective chart review. SUBJECTS Children aged 3 years and younger who underwent PSG to evaluate obstructive sleep apnea and subsequently underwent adenotonsillec...

2014
J. A. Pérez-Fidalgo B. Bermejo I. Chirivella M. T. Martínez I. González J. M. Cejalvo I. Catoira P. Martínez E. Contel A. Lluch

PURPOSE To evaluate the impact on survival of the relative dose intensity (RDI) achieved in patients with early breast cancer receiving anthracycline plus taxane-based chemotherapy in the adjuvant setting. PATIENTS AND METHODS Patients with early breast cancer diagnosed from January 1999 through December 2006 were included. Dose intensity was evaluated according to the number of delayed cycle...

2015
Antonio Gutiérrez Leyre Bento Antonia Maria Bautista-Gili Francesc Garcia Jordi Martinez-Serra Blanca Sanchez Clara Martorell Jordi Gines Lucia Garcia Eva Gimeno Mariana Ferraro Raquel Del Campo Joan Bargay Albert Perez Javier Vercher Miguel Scaff Ana Pacheco Carmen Ballester Florencia Garcia Rafael Ramos Antonio Salar Joan Besalduch

DLBCL is an aggressive lymphoma treated with R-CHOP. Recently, attempts have been made to improve the outcome by increasing both dose-density and intensity but there have been no benefits in terms of survival. When treating malignancies RDI is important to consider but there is little published information on DLBCL. The purpose of this study was to analyze the differential prognostic impact of ...

2002
Stuart F. Quan

THE MOST COMMONLY USED INDICATOR OF SLEEP DISORDERED BREATHING (SDB) SEVERITY IS THE RESPIRATORY DISTURBANCE INDEX (RDI), WHICH IS SYNONYMOUS WITH THE APNEA HYPOPNEA INDEX (AHI) IN MANY REPORTS. The RDI is the total number of apneas and hypopneas per hour of sleep. In clinical populations, the RDI is used to define the presence of SDB and thus identify individuals who require treatment.1,2 In a...

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