OBJECTIVES This study sought to investigate the safety and efficacy of transcatheter treatment of atrial septal aneurysm (ASA) associated with patent foramen ovale (PFO). BACKGROUND Patients with both ASA and PFO are at high risk for recurrent paradoxical embolism. METHODS The procedural, echocardiographic, and clinical outcomes of 141 patients with ASA + PFO and > or =1 paradoxical embolic...

The surgical management of Knee Osteoarthritis (KOA), so far, mainly revolved around arthroscopic procedures,arthroplasty (total: TKA and unicompartmental: UKA) or high tibial osteotomy (HTO). Recently, another minimallyinvasive surgical treatment of proximal fibular osteotomy (PFO) has been proposed for the management of KOA. ThePFO has been found to be useful in the manageme...

BACKGROUND To evaluate the incidence, frequency, and contributing factors of microembolic signals (MESs) in patients with cryptogenic stroke with or without patent foramen ovale (PFO). METHODS Transcranial Doppler monitoring for MESs detection was performed for 62 patients with acute cryptogenic stroke with PFO (PFO(+)) and 34 patients with acute cryptogenic stroke without PFO (PFO(-)). RES...

The prevalence of a patent foramen ovale (PFO) is ~30%, and this source of right-to-left shunt could result in greater pulmonary gas exchange impairment at rest and during exercise. The aim of this work was to determine if individuals with an asymptomatic PFO (PFO+) have greater pulmonary gas exchange inefficiency at rest and during exercise than subjects without a PFO (PFO-). Separated by 1 h ...

BACKGROUND A causal relationship between patent foramen ovale (PFO) and migraine has been hypothesized, and improvement of migraine frequency and severity after percutaneous PFO closure has been reported. Population-based data on the relationship between PFO and migraine are sparse, however. The objective of this study was to examine the association between PFO and migraine among stroke-free in...

Background—A causal relationship between patent foramen ovale (PFO) and migraine has been hypothesized, and improvement of migraine frequency and severity after percutaneous PFO closure has been reported. Population-based data on the relationship between PFO and migraine are sparse, however. The objective of this study was to examine the association between PFO and migraine among stroke-free in...

BACKGROUND The present study aimed to determine lesion patterns and the stroke mechanisms in cryptogenic ischemic stroke patients with patent foramen ovale (PFO) on T2-weighted magnetic resonance imaging (T2WI) and fluid-attenuated inversion recovery (FLAIR) sequences combined. METHODS In this retrospective study, 38 patients with cryptogenic stroke and an isolated PFO compared with 51 crypto...

BACKGROUND AND PURPOSE Patent foramen ovale (PFO) is a frequent finding in young patients with stroke. The aim of this study was to assess whether PFO is a family trait. METHODS Sixty-two consecutive patients younger than 60 years of age with ischemic stroke and 62 age and gender-matched control siblings were examined by means of contrast transcranial Doppler (TCD) of the middle cerebral arte...

BACKGROUND Despite the diffusion into practice of percutaneous closure of a patent foramen ovale (PFO) in patients with cryptogenic stroke (CS), the benefits have not been demonstrated, and remain unclear. For any individual presenting with a PFO in the setting of CS, it is not clear whether the PFO is pathogenically-related to the index event or an incidental finding. Further, the overall rate...

BACKGROUND AND PURPOSE Patent foramen ovale (PFO) and cryptogenic stroke are commonly associated but some PFOs are incidental. Specific radiological findings associated with PFO may be more likely to indicate a PFO-related cause. We examined whether specific radiological findings are associated with PFO among subjects with cryptogenic stroke and known PFO status. METHODS We analyzed the Risk ...