background: the induction of brain-derived neurotrophic factor (bdnf) expression in the hippocampus has shown to play a role in the beneficial effects of resveratrol (rsv) on the learning and memory. the bdnf gene has a complicated structure with eight 5’ noncoding exons (i-ixa), each of which can splice to a common coding exon (ix) to form a functional transcript. estrogens increase levels of ...

background: it has been known that brain-derived neurotrophic factor (bdnf) is involved in neural survival and long term memory (ltm). here we hypothesized that bdnf as a potent neurotrophic factor might modulate amnestic effect induced by morphine. objectives: the aim of this study was to examine whether infusion of exogenous bdnf in the ca1 regions of the dorsal hippocampi could ameliorate me...

as the middle-aged in the society as well as stress-induced cognitive disorders and dementia are increasing, sport is identified as a suitable solution to prevent disorders in central nervous system. the aim of the present study was to compare the effects of 8 weeks of strength and endurance training on bdnf. for this purpose, 150 male wistar rats participated in endurance training (running wit...

Brain-derived neurotrophic factor (BDNF) is known to play a role in experience-dependent plasticity of the developing visual cortex. For example, BDNF acutely enhances long-term potentiation and blocks long-term depression in the visual cortex of young rats. Such acute actions of BDNF suggested to be mediated mainly through presynaptic mechanisms. A chronic application of BDNF to the visual cor...

Brain-derived neurotrophic factor (BDNF) is known to play a role in experience-dependent plasticity of the developing visual cortex. For example, BDNF acutely enhances long-term potentiation and blocks long-term depression in the visual cortex of young rats. Such acute actions of BDNF suggested to be mediated mainly through presynaptic mechanisms. A chronic application of BDNF to the visual cor...

Introduction: Ramadhan fasting increases mental and physical health. The study aims to evaluate the effect of on fatigue, sleepiness, depression anxiety mood, quality life (QoL), Brain-derived neurotrophic factor (BDNF) serum level.
 Methods: Twenty participants are included in group (FG), nineteen non-fasting (NFG). Fatigue severity scales (FSS), fatigue VAS, Epworth sleepiness scale (ESS...