نتایج جستجو برای: موتیف ape

تعداد نتایج: 2566  

Journal: :Cardiology journal 2012
Leszek Gromadziński Ryszard Targoński Beata Januszko-Giergielewicz Michał Ciurzyński Piotr Pruszczyk

BACKGROUND Patients with acute pulmonary embolism (APE) with concomitant chronic heart failure (CHF) are characterized by higher mortality rates than APE patients without CHF. The aim of this study is to evaluate the potential impact of APE on early and long-term prognosis in patients with CHF. METHODS This study included 87 patients with CHF with suspected APE. Patients were divided into two...

2014
ZHEN YANG SUN YANG BOBBYE J. MISNER FENG LIU-SMITH FRANK L. MEYSKENS

Hepatocellular carcinoma (HCC) is responsible for a third of the estimated cancer-caused deaths worldwide. To deeply understand the mechanisms controlling HCC progression is of primary importance to develop new approaches for treatment. Apurinic/apyrimidinic endonuclease-1/redox effector factor 1 (APE/Ref-1) has been uncovered elevated in various types of cancer, including HCC. Additionally, HC...

Journal: :Cancer research 2010
Ranajoy Chattopadhyay Asima Bhattacharyya Sheila E Crowe

Human apurinic/apyrimidinic endonuclease-1 (APE-1), a key enzyme involved in repair of oxidative DNA base damage, is an important transcriptional coregulator. We previously reported that Helicobacter pylori infection induces apoptosis and increases APE-1 expression in human gastric epithelial cells (GEC). Although both the DNA repair activity and the acetylation-mediated transcriptional regulat...

Journal: :Circulation journal : official journal of the Japanese Circulation Society 2014
Masaaki Konishi Yasushi Matsuzawa Hiroyuki Suzuki Eiichi Akiyama Noriaki Iwahashi Nobuhiko Maejima Mitsuaki Endo Kengo Tsukahara Kiyoshi Hibi Masami Kosuge Toshiaki Ebina Kentaro Sakamaki Satoshi Morita Satoshi Umemura Kazuo Kimura

BACKGROUND  Acute pulmonary edema (APE) often occurs without remarkable fluid retention, and the benefits of diuretics are unclear in such patients. Although aggressive diuresis induces an increase in intravascular substances including hemoglobin (Hb), acute changes in Hb level remain to be investigated. METHODS AND RESULTS  We analyzed 237 consecutive acute heart failure patients (74±12 year...

Journal: :British journal of anaesthesia 2012
B E Winkler W Schuetz G Froeba C-M Muth

BACKGROUND Acute pulmonary embolism (APE) is an important clinical problem in patients after major surgery and often remains a difficult diagnosis because of unspecific clinical symptoms. Therefore, we investigated the role of N-terminal prohormone of brain natriuretic peptide (NT-proBNP) for the detection of APE. METHODS In 44 patients with suspected APE referred to the intensive care unit a...

Journal: :African health sciences 2014
Fahrettin Talay Tarık Ocak Aytekin Alcelik Kurşat Erkuran Akcan Akkaya Arif Duran Abdullah Demirhan Ozlem Kar Kurt Zehra Asuk

OBJECTIVE To investigate the diagnostic importance of mean platelet volume (MPV) on acute pulmonary embolism (APE) in the emergency Department (ED). METHODS Subjects were selected from patients admitted to ED with clinically suspected APE. Demographic, anthropometric and serologic data were collected for each patient. RESULTS A total of 315 consecutive patients were analyzed, including 150 ...

Journal: :European review for medical and pharmacological sciences 2016
S T Onur S Emet S Surmen K Kara M Kose H Oflaz I Onur

OBJECTIVE Acute pulmonary embolism (APE) is a very common disease that must be diagnosed and treated quickly and accurately to reduce significant morbidity and mortality rates. Acute pulmonary embolism is associated with numerous electrocardiographic (ECG) changes including prolonged QT interval with global T-wave inversion. The aim of the study was to investigate the relationship between the T...

Journal: :Science 1981

"موتیف" یکی از پربسامدترین واژگان نقد ادبی معاصر به تکرار موسیقی­وار و نظام­مند برخی از سازه­ها از قبیل جمله، عبارت، واژه، اصطلاح در متن اطلاق می­شود که در شکل­دهی به محتوا و سبک اثر نقش دارد. در متون روایی با شناخت موتیف می­توان به درون­مایه و سبک اثر پی­برد و همچنین به­کارگیری موتیف روشی برای ایجاد انسجام و پیوستگی در متن است. پژوهش حاضر در تلاش است موتیف "أرض" (زمین)، جلوه‌ها و کارکردهای آن ...

2018
Danny Epstein Gidon Berger Noam Barda Erez Marcusohn Yuval Barak-Corren Khitam Muhsen Ran D Balicer Zaher S Azzam

BACKGROUND A recently published, large prospective study showed unexpectedly high prevalence of acute pulmonary embolism (APE) among patients hospitalized for syncope. In such a case, a high incidence of recurrent pulmonary embolism is expected among patients who were discharged without APE workup. OBJECTIVES To determine the incidence of symptomatic APE among patients hospitalized for a firs...

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