نتایج جستجو برای: معیار bic
تعداد نتایج: 29932 فیلتر نتایج به سال:
BACKGROUND The influences of potential bone-to-implant contact (BIC) area (pBICA), BIC area (BICA), and three dimensional (3D) BIC percentage (3D BIC%; defined as BICA divided by pBICA) in relation to the implant length on initial implant stability were studied. Correlations between these parameters were also evaluated. METHODS Implants with lengths of 8.5, 10, 11.5, and 13 mm were placed in ...
Bictegravir (BIC; GS-9883), a novel, potent, once-daily, unboosted inhibitor of HIV-1 integrase (IN), specifically targets IN strand transfer activity (50% inhibitory concentration [IC50] of 7.5 ± 0.3 nM) and HIV-1 integration in cells. BIC exhibits potent and selective in vitro antiretroviral activity in both T-cell lines and primary human T lymphocytes, with 50% effective concentrations rangi...
Cytochrome P450 46A1 (CYP46A1) is the cholesterol 24-hydroxylase initiating the major pathways of cholesterol removal from the brain, and bicalutamide (BIC) is a drug of choice for the treatment of progressive androgen-dependent prostate cancer. We evaluated the interactions of BIC with CYP46A1 by x-ray crystallography and by conducting solution and mutagenesis studies. Because BIC is administe...
We previously demonstrated high expression of primary-microRNA BIC (pri-miR-155) in Hodgkin lymphoma (HL) and lack of expression in most non-Hodgkin lymphoma subtypes including some Burkitt lymphoma (BL) cases. Recently, high expression of BIC was reported in BL in comparison to pediatric leukemia and normal peripheral-blood samples. In this study, we extended our series of BL cases and cell li...
The known dimensions of hydrothermal fluid circulation associated with emplacement of the 2.055-Ga Bushveld Igneous Complex (BIC) are extended with new isotopic ages for Paleoproterozoic mineral deposits in wallrocks (Transvaal Supergroup) surrounding the BIC. A fluorite-rich Mississippi Valley–type (MVT) deposit in the Zeerust district, dated at 2.05 Ga (Sm-Nd isochron age), has Nd isotopic co...
In our previous work[18], it was proved that the performance of bic-tcp was good under satellite network, and a new adaptive window increment based bic-tcp algorithm (bic_AWI) was proposed to show an improved data transfer in satellite network. We, implemented the idea on ns2’s implementation of bic tcp. Proposed modifications has been made on bic-tcp, and improvement in performance has been re...
Body image concerns: levels, correlates and gender differences among students in the United Kingdom.
AIMS This cross-sectional study aimed to determine the socio-demographic, lifestyle and well-being variables that are associated with body image concerns (BIC) and whether these associations differed between female and male students. METHODS A cross-sectional survey; 3,706 undergraduate students (2,699 females, 765 males) from seven universities in the UK completed a self-administered questio...
To be therapeutically active, oral hyperimmune bovine immunoglobulin concentrate (BIC) must survive its passage through the intestinal tract. This led us to study the gastrointestinal stability of orally administered BIC directed against Clostridium difficile toxins (BIC-C. difficile). BIC-C. difficile was stable at neutral pH in vitro but was degraded at low pH, particularly in the presence of...
The Xenopus Cripto-1 protein is confined to the cells of the animal hemisphere during early embryogenesis where it regulates the formation of anterior structures. Cripto-1 protein accumulates only in animal cells because cripto-1 mRNA in cells of the vegetal hemisphere is translationally repressed. Here, we show that the RNA binding protein, Bicaudal-C (Bic-C), functioned directly in this veget...
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