UNLABELLED Ruthenium (Ru) complexes are currently the focus of substantial interest because of their potential application as chemotherapeutic agents with broad anticancer activities. This study investigated the in vitro and in vivo anticancer activities and mechanisms of two Ru complexes-2,3,7,8,12,13,17,18-Octaethyl-21H,23H-porphine Ru(II) carbonyl (Ru1) and 5,10,15,20-Tetraphenyl-21H,23H-por...

The interaction of enantiomerically pure dinuclear complexes of the form [Ru2(L-L)4L1]4+ (where L-L = 2,2'-bipyridine (bpy) or 1,10-phenanthroline (phen) and L1 = bis(pyridylimine) ligand ((C5H4N)CN(C6H4))2CH2)) with ct-DNA have been investigated by absorbance, circular dichroism, fluorescence displacement assays, thermal analysis, linear dichroism and gel electrophoresis. The complexes all bin...

A series of paddlewheel diruthenium(ii, ii) complexes with various chlorine-substituted benzoate ligands (Cl-series) was synthesized as tetrahydrofuran (THF) adducts [Ru2(ClxPhCO2)4(THF)2]; where ClxPhCO2(-) = o-chlorobenzoate, ; m-chlorobenzoate, ; p-chlorobenzoate, ; 2,3-dichlorobenzoate, ; 2,4-dichlorobenzoate, ; 2,5-dichlorobenzoate, ; 2,6-dichlorobenzoate, ; 3,4-dichlorobenzoate, ; 3,5-dic...

Let (RU1, RU2) be a given bivariate scale mixture random vector, with R > 0 being independent of the bivariate random vector (U1, U2). In this paper we derive exact asymptotic expansions of the tail probability P{RU1 > x, RU2 > ax}, a ∈ (0, 1] as x → ∞ assuming that R has distribution function in the Gumbel max-domain of attraction and (U1, U2) has a specific tail behaviour around some absorbin...

We report an approach to reduce grain size for perpendicular media by using an Ar-ion etched Ru seedlayer. The surface etching affects the microstructure of the subsequent high pressure deposited Ru2+SiO2 interlayer and magnetic layer, whose grain size can be controlled. SiO2 in the interlayer plays a more important role in grain size reduction on the etched seedlayer than the as-grown seedlaye...

We report on the magnetic structures of ${\mathrm{Tb}}_{3}{\mathrm{RuO}}_{7}$ and ${\mathrm{Nd}}_{3}{\mathrm{RuO}}_{7}$ determined from powder neutron-diffraction experiments. In ${\mathrm{Tb}}_{3}{\mathrm{RuO}}_{7}$, alternating-bond spin-$\frac{3}{2}$ Ru1-Ru2 chains are formed. The Ru1 Ru2 moments ordered disordered (paramagnetic), respectively, below 15 K. This result indicates appearance a ...

The synthesis and structural characterization of the complex [Ru2(μ-Cl)(μ-P Bu2)(μ-dppa)(CO)4] (4, dppa = Ph2PN(H)PPh2) are reported. The title compound and two other related complexes were obtained in high yields by the reaction of the coordinatively unsaturated species [Ru2(μ-H)(μ-P Bu2)(μ-PˆP)(CO)4] (PˆP = dppa, 3; PˆP = Ph2PN(Ph)PPh2, 5; PˆP = Ph2PN(CH2Ph)PPh2, 6) with carbon tetrachloride....

The oxalato complexes [Ru2(μ-η -C2O4)Cl2(η -p-PrC6H4Me)2] 1 and [Ru(η -C2O4)(NH3)(η -p-PrC6H4Me)] 2 have been prepared from the reaction of ammonium oxalate with [{RuCl2(η -p-PrC6H4Me)}2] and [Ru(H2O)3(η-p-PrC6H4Me)] , respectively. With triphenylphosphine, 1 reacted to give [Ru2(μ-η -C2O4)(PPh3)2(η -p-PrC6H4Me)2] 21 3, while 2 gave [Ru(η-C2O4)(PPh3)(η -p-PrC6H4Me)] 4. The dichloro complex 1 ca...

The thermal reaction of Ru3(CO)12 with the biologically active acids acetyl salicylic acid (Aspirin), a-methyl-4-(isobutyl)phenylacet acid (Ibuprofen) and 3a,7a,12a-trihydroxy-5b-cholanic acid (cholic acid) in refluxing tetrahydrofuran, followed by addition of tripheny phosphine, gives the dinuclear complexes Ru2(CO)4(OOCR)2(PPh3)2 (1: R = C6H4-2-OCOMe, 2: R = CHMe-C6H4-4-Bu , 3: C23H39O3 The s...