Postoperative Cognitive Dysfunction (POCD) is associated with increased mortality in the elderly and may occur from lipid peroxidation in aging. We previously showed that sevoflurane sequesters acrolein, which promotes the formation of a novel species of a putative neuromelanin. The current study examined the properties of this serotonin-derived melanoid (SDM). The interaction of SDM with unila...

Shared decision-making (SDM) occurs when patients, families and clinicians consider patients' values and preferences alongside the best medical evidence and partner to make the best decision for a given patient in a specific scenario. SDM is increasingly promoted within Western contexts and is also being explored outside such settings, including in China. SDM and tools to promote SDM can improv...

PURPOSE The SDM-Q-9 and SDM-Q-Doc measure patient and physician perception of the extent of shared decision making (SDM) during a physician-patient consultation. So far, no self-report instrument for SDM was available in Dutch, and validation of the scales in other languages has been limited. The aim of this study was to translate both scales into Dutch and assess their psychometric characteris...

As the paradigm in healthcare nowadays is the evidence-based, patient-centered decision making, the issue of shared decision making (SDM) is highlighted. The aims of this manuscript were to look at the relevant concepts and suggest the facilitating strategies for overcoming barriers of conducting SDM. While the definitions of SDM were discordant, several concepts such as good communication, ind...

The implementation on hardware of the first layer of Kanerva’s sparse distributed memory (SDM) is presented in this work. The hardware consist on a co-processor board for connection on ISA standard bus of an IBM–PCcompatible computer. The board, named reconfigurable co-processor for SDM(RC-SDM), comprises on Xilinx FPGAs, local random access memory and bus interface circuits. Based on in-system...

Progress is reported in parametrically controlled noise shaping sigma delta modulator (SDM) design. As this SDM structure can provide a higher SNR than normal SDM structures, Philips Research Laboratories questioned whether further improvement could be obtained using techniques inspired by the Trellis SDM. Simulations are used here to illustrate the performance of a parametrically controlled ps...

BACKGROUND AND METHODOLOGY Replicating a Peruvian study, this research introduced the Standard Days Method (SDM) into Rwanda Ministry of Health clinics and evaluated client counselling on the new method against that given for contraceptive pills. Providers received technical reinforcement concerning established methods in addition to SDM training. To evaluate their quality of care, simulated cl...

101 A New Approach to Kanerva's Sparse Distributed Memory Tim A. Hely, David J. Willshaw, and Gillian M. Hayes Abstract|The Sparse Distributed Memory (SDM)[1] was originally developed to tackle the problem of storing large binary data patterns. The model succeeded well in storing random input data. However its e ciency, particularly in handling non{random data, was poor. In its original form it...

The state-of-the-art OpenFlow technology only partially realized SDN vision of abstraction and centralization for packet forwarding in switches. OpenFlow/P4 falls short in implementing middlebox functionalities due to the fundamental limitation in its match-action abstraction. In this paper, we advocate the vision of Software-Defined Middleboxes (SDM) to realize abstraction and centralization f...

Objective Shared decision-making (SDM) is the process by which patients, clinicians, and in pediatrics, parents/caregivers, discuss treatment options, communicate available evidence for or against the different options, share preferences and values, and eventually arrive at a joint decision. This study evaluates the use of a novel, universally applicable, SDM intervention, provided to parents, ...