Duchenne muscular dystrophy (DMD) is the most common form of muscular dystrophy. DMD patients lack dystrophin protein and develop skeletal muscle pathology and dilated cardiomyopathy (DCM). Approximately 20% succumb to cardiac involvement. We hypothesized that mesoangioblast stem cells (aorta-derived mesoangioblasts [ADMs]) would restore dystrophin and alleviate or prevent DCM in animal models ...

Koza has previously shown that the power of a genetic programming system can often be enhanced by allowing for the simultaneous evolution of a main program and a collection of automatically de ned functions (ADFs). In this paper I show how related techniques can be used to simultaneously evolve a collection of automatically de ned macros (ADMs). I show how ADMs can be used to produce new contro...

Monoisoamyl meso-2,3-dimercaptosuccinate (Mi-ADMS) was found to be superior to meso-2,3-dimercaptosuccinic acid (DMSA) in decreasing the body burden of 203Hg in rats under conditions of early treatment. In this experiment Mi-ADMS was used as late treatment for mercury removal. Albino rats aged 6 weeks and 7-day-old sucklings received a single intraperitoneal injection of 203Hg (as nitrate). Two...

BACKGROUND Tissue reinforcement with allogeneic or xenogeneic acellular dermal matrices (ADMs) is increasingly used in single-stage (direct-to-implant) and 2-stage implant-based breast reconstruction following mastectomy. ADMs allow surgeons to control implant position and obviate the need for submuscular implant placement. Here, we review the benefits and risks of using ADMs in implant-based b...

Introduction: In traffic grooming, the lower bounds on the numbers of ADMs and wavelengths are important parameters in evaluating the grooming results. Although much work has been done on the grooming of traffic in WDM ring networks and the lower and upper bounds on the number of wavelengths and the upper bound on that of ADMs are relatively easy to derive, the lower bound on the number of ADMs...

Autonomous distributed manufacturing systems(ADMS) consist of multiple intelligent components with each component acting according to its own judgments. The ADMS objective is to realize more agile and adaptive manufacturing systems. This paper presents the introduction of context-dependent agents (CDAs) in ADMS that switch strategies depending on system conditions to achieve better performance ...

BACKGROUND Acellular dermal matrices (ADMs) are frequently used in reconstructive surgery and as scaffolds to treat chronic wounds. The 3-dimensional architecture and extracellular matrix provide structural and signaling cues for repair and remodeling. However, most ADMs are not uniformly porous, which can lead to heterogeneous host engraftment. In this study, we hypothesized that a novel human...

The goal of the ADMS project is to create a framework for caching materialized views, access paths, and experience obtained during query execution. The rationale behind this project is to amortize database access cost over an extended time period and adapt execution strategies based on experience. ADMS demonstrates the versatility of the views and their role in performance, data warehousing, ma...

We consider the problem of traffic grooming in wavelength-divisionmultiplexing rings with all-to-all uniform traffic. Our objective is to minimize the total number of electronic add–drop multiplexers (ADMs) required. We derive explicit optimal solutions for two special cases: one with a traffic granularity of 4 and the other with 16. When the traffic granularity is equal to 4, we also show that...