Nonalcoholic fatty liver disease is the most common chronic liver disease, which can progress to nonalcoholic steatohepatitis (NASH). Previous investigations demonstrated alterations in the expression and activity of hepatic drug transporters in NASH. Moreover, studies using rodent models of cholestasis suggest that compensatory changes in kidney transporter expression occur to facilitate renal...

use for each and every act of intercourse.4 The use of condoms is recommended for individuals who have multiple partners, who have a primary partner who is infected, or who have a partner whose serostatus is unknown,5 although the absolute amount of protection they provide has not been accurately established. The effectiveness of the condom as a contraceptive provides insight into its usefulnes...

ical—i.e., that a pregnant teenager who is still growing may be competing for nutrients with the fetus, or that pregnancy within two years after menarche increases the risk of preterm delivery.4 Psychological factors may also be involved, since many adolescent pregnancies are unplanned, unwanted or discovered late;5 a pregnant teenager may lack the emotional maturity to take responsibility for ...

INTRODUCTION The relationship between growth in population and consumption and common-pool resources, particularly those that are governed under common-property institutions, has been the subject of lively academic debate. Researchers have long dwelled upon the global demographic transition and its effect on land-tenure and inheritance practices in different regions of the world. Boserup postul...

misson on Ordovician Stratigraphy and in 2002 ratified by the International Commission on Stratigraphy as the GSSP of the Second (Upper) Stage of the Lower Ordovician, is located on the Hunneberg Mountain in southwestern Sweden. The stratigraphic succession represents an outer shelf environment near the Baltic Shield margin. The shale-dominated, biostratigraphically complete, richly fossilifero...