PURPOSE Endothelial progenitor cells (EPCs) are present in circulation and contribute to vasculogenesis in adults. We measured the number of circulating EPCs in patients with myelofibrosis with myeloid metaplasia (MMM), and we examined the relationship between the number of EPCs and severity of the MMM disease process. PATIENTS AND METHODS The number of EPCs was measured by assaying the CD34+...

MOTIVATION Accurate alignment of a target sequence to a template structure continues to be a bottleneck in producing good quality comparative protein structure models. RESULTS Multiple Mapping Method (MMM) is a comparative protein structure modeling server with an emphasis on a novel alignment optimization protocol. MMM takes inputs from five profile-to-profile based alignment methods. The al...

The JAK2V617F mutation is present in most patients with polycythemia vera (PV) and in some patients with essential thrombocythemia (ET) and myeloid metaplasia/myelofibrosis (MMM). We sought to investigate the relationship between granulocyte clonality and JAK2V617F allelic ratio. A total of 168 of 190 female patients were informative for a clonality assay at the HUMARA locus; 80% of MMM, 75% of...

The new concept of multinode moment matching (MMM) is introduced in this paper. The MMM technique simultaneously matches the moments at several nodes of a circuit using explicit moment matching around = 0. As compared to the well known single-point moment matching (SMM) techniques (such as asymptotic waveform evaluation), MMM has several advantages. First, the number of moments required by MMM ...

It has been proved by experiments that the metal magnetic memory (MMM) NDT method can effectively detect the stress concentration of ferromagnetic metal parts. But it is still hard to evaluate the stress concentration quantitatively because of the confusion in the mechanism of MMM method. In this paper experiments are designed and carried out to investigate the relationship between the MMM sign...

Number 51 Recently, President Reagan signed a bill to reduce federal spending over the next three years by $130 billion. Almost as soon as the ink dried, Administration officials announced that further reductions totaling about $75 billion were needed to erase the federal budget deficit by 1984. Subsequently, it became evident that even that was not enough. It is clear that these budget plans w...

Twenty-two patients with primary myeurinary hemosiderin. The defects of lofibrosis and myeloid metaplasia the red cell membrane, as evidenced (MMM) and ten patients with MMM by acid and sucrose lysis tests, were secondary to carcinoma were studied limited to those with primary MMM and for the relationship of MMM to “PNHoccurred in 54#{176}/o of the cases. Another like defect.” Laboratory measur...

The splenic architecture is essential for the quick resolution of a primary infection with Plasmodium. A critical component of this architecture is the marginal zone (MZ), an area of the spleen that separates the reticuloendothelial red pulp of the spleen from the lymphoid white pulp compartment. There are two unique macrophage populations found in the MZ: MZ macrophages (MZM) found on the oute...

PURPOSE OF REVIEW Multimodal monitoring (MMM) is routinely applied in neurointensive care. Unfortunately, there is no robust evidence on which MMM-derived physiologic variables are the most clinically relevant, how and when they should be monitored, and whether MMM impacts outcome. The complexity is even higher because once the data are continuously collected, interpretation and integration of ...