We have previously demonstrated that DT-010, a novel conjugate of danshensu (DSS) and tetramethylpyrazine (TMP), displays anti-tumor effects in breast cancer cells both in vitro and in vivo. In the present study, we investigated whether DT-010 enhances the chemotherapeutic effect of doxorubicin (Dox) in MCF-7 breast cancer cells and exerts concurrent cardioprotective benefit at the same time. O...

In repeated games with di®erential information on one side, the labelling \general case" refers to games in which the action of the informed player is not known to the uninformed, who can only observe a signal which is the random outcome of his and his opponent's action. Here we consider the problem of minimizing regret (in the sense ̄rst formulated by Hannan [8]) when the information available...

Akita Research Institute of Food and Brewing 4-26 Sanuki, Arayamachi, Akita 010-1623, Japan Faculty of Bioresource Sciences, Akita Prefectural University 241-438, Kaidobata-Nishi, Nakano, Shimoshinjo, Akita 010-0195, Japan Agricultural Experiment Station Akita Prefectural Agriculture, Forestry and Fisheries Research Center 34-1 Gennpachizawa, Aikawa, Yuwa, Akita 010-1231, Japan Department of En...

Chinese city-level data indicate that differences in growth rates are far more severe at this level than indicated in previous studies which typically use data at higher levels of aggregation. Using city-level data for 206 cities during 1989 to 1996, we estimate a variety of growth equations. A major finding is that while the policy of awarding a special economic zone status enhances growth (wi...

The mitochondrial respiratory chain, including mitochondrial complex II, has emerged as a potential target for cancer therapy. In the present study, a novel conjugate of danshensu (DSS) and tetramethylpyrazine (TMP), DT-010, was synthesized. Our results showed that DT-010 is more potent than its parental compounds separately or in combination, in inhibiting the proliferation of MCF-7 and MDA-MB...

The Journal of Economic Literature codes classification system (JEL) published by the American Association (AEA) is de facto standard for research literature in economics. JEL used to classify articles, dissertations, books, book reviews, and working papers EconLit, a database maintained AEA. Over time, it has evolved extended with over 850 subclasses. This paper reviews history development sys...

Foreign aid has often been intended by donors to entice recipient nations into policy and institutional reforms favorable to private sector economic development. In this study, we investigate the relationship between aid and changes to economic freedom in recipient nations over the 1990–2000 decade. The evidence is mixed. In general, we find that foreign aid has no significant effect on economi...