global warming has brought about changes in meteorological variable time series. these changes, accompanied with serious human intervention in nature, has resulted in hydrological changes. so the effects can be tracked down by the trend of the time series. the purpose of this study is to analyze and compare the monthly and annual trends of temperature, precipitation as well as stream flow time ...

We analyze M-theory compactified on (K3 × S)/Z2 where the Z2 changes the sign of the three form gauge field, acts on S as a parity transformation and on K3 as an involution with eight fixed points preserving SU(2) holonomy. At a generic point in the moduli space the resulting theory has as its low energy limit N = 1 supergravity theory in six dimensions with eight vector, nine tensor and twenty...

The flesh-eating bacterium group A Streptococcus (GAS) binds and activates human plasminogen, promoting invasive disease. Streptococcal surface enolase (SEN), a glycolytic pathway enzyme, is an identified plasminogen receptor of GAS. Here we used mass spectrometry (MS) to confirm that GAS SEN is octameric, thereby validating in silico modeling based on the crystal structure of Streptococcus pne...

The demand for privacy of digital data and of algorithms for handling more complex structures have increased exponentially over the last decade. This goes in parallel with the growth in communication networks and their devices and their increasing capabilities (Sen, 2013a; Sen, 2012d; Sen, 2012c; Bandyopadhyay & Sen, 2011; Sen, 2011b; Sen, 2011c; Sen, 2010c). At the same time, these devices and...

The hallmark of transmissible spongiform encephalopathies (TSEs or prion diseases) is the accumulation of an abnormally folded, partially protease-resistant form (PrP-res) of the normal protease-sensitive prion protein (PrP-sen). PrP-sen is attached to the cell membrane by a glycosylphosphatidylinositol (GPI) anchor. In vitro, the anchor and the local membrane environment are important for the ...

Recently, a novel DNA virus designated SEN virus (SEN-V), which is thought to be related to posttransfusion hepatitis, was discovered. The aim of the present study was to clarify the relationship between SEN-V infection and the development of liver disease. We examined SEN-V from the sera of 21 patients with non-B, non-C hepatocellular carcinoma (HCC) and 13 patients with non-B, non-C chronic l...

Aim: A recently discovered DNA virus (SEN virus) has been assumed to be responsible for posttransfusion hepatitis in humans. Phylogenetic analysis of the SEN virus (SEN-V) has revealed the existence of 8 different genotypes (A-H). SEN-V genotype-H (SENV-H) and SEN-V genotype-D (SENV-D) have been described as most closely associated with post-transfusion hepatitis. So far, it is unclear whether ...