This study's main objective was to determine if upper-limb (UL) muscular demand was reduced when individuals with a spinal cord injury (SCI) performed a sitting pivot transfer (SPT) in the preferred direction compared with that in a nonpreferred direction. Fourteen individuals (mean +/- standard deviation age 47.0 +/- 8.3 yr, height 1.80 +/- 0.08 m, and weight 75.3 +/- 11.3 kg) with SCI levels ...

It has been hypothesized that bacterial debris may accumulate in tissues of the reticuloendothelial system (RES) serving as an inflammatory stimulus for human disease. In support of this hypothesis, muramic acid (Mur), a component of bacterial peptidoglycan (PG), has previously been reported to be present in culture-negative human spleen. High-performance liquid chromatography (HPLC) was employ...

Muramic acid (Mur) is present in the cell wall of Eubacteria and serves as a chemical marker for the trace detection of bacteria and bacterial cell wall debris in complex matrices. There have been numerous studies using a variety of derivatives of Mur, particularly in combination with gas chromatography-tandem mass spectrometry (GC-MS-MS) where the detection limit has been steadily lowered. A s...

ATP-dependent Mur ligases (Mur synthetases) play essential roles in the biosynthesis of cell wall peptidoglycan (PG) as they catalyze the ligation of key amino acid residues to the stem peptide at the expense of ATP hydrolysis, thus representing potential targets for antibacterial drug discovery. In this study we characterized the division/cell wall (dcw) operon and identified a promoter drivin...

BACKGROUND Current evidence supports the benefit of medicine-use review (MUR) for the safe and effective use of medicines. However, little is known about opinions of consumers regarding their preference for undertaking MUR, especially in the developing world, eg, in some Asian countries. We aimed to explore patients' opinions about potential MUR and other enhanced services provided by community...

BACKGROUND The recent X-ray crystal structure of the murine μ-opioid receptor (MUR) allowed the authors to reengineer a previously designed water-soluble variant of the transmembrane portion of the human MUR (wsMUR-TM). METHODS The new variant of water-soluble MUR (wsMUR-TM_v2) was engineered based on the murine MUR crystal structure. This novel variant was expressed in Escherichia coli and p...

Computer Systems Laboratory Stanford University Email: [email protected] Abstract. This is a brief overview of the Mur' verification system. The Mur' description language Mur' is both a description language and a verifier for finite state concurrent systems [DDHY92]. It is appropriate for protocols and finite-state systems which can reasonably be modelled as a collection of processes that ru...