We conducted a placebo-controlled, double-blind, randomized study to evaluate the microbiological efficacy and safety of inhaled tobramycin for treatment of patients with bronchiectasis and Pseudomonas aeruginosa. Patients were randomly assigned to receive either tobramycin solution for inhalation (TSI) (n = 37) or placebo (n = 37), which was self-administered twice daily for 4 wk and followed ...

BACKGROUND The Teacher Stress Inventory (TSI) is an instrument for measuring occupational stress in teachers. This study aimed to translate and adapt it for use in Greece, and then assess its reliability and validity. METHODS The Greek versions of the TSI and the 14-item Perceived Stress Scale (PSS-14) were posted on all Greek educators' official sites during May 2012. A nationwide sample of ...

Vibrio cholerae O1 strain TSI-4 (El Tor, Ogawa) can shift to a rugose colony morphology from its normal translucent colony morphology in response to nutrient starvation. We have investigated differences between the rugose and translucent forms of V. cholerae O1 strain TSI-4. Electron microscopic examination of the rugose form of TSI-4 (TSI-4/R) revealed thick, electron-dense exopolysaccharide m...

We have explored the method of Rapoport et al. (J Clin Endocrinol Metab 1984;58:332-8) for the bioassay of thyroid-stimulating immunoglobulin (TSI) in cultured human thyroid cells, to optimize the assay and to evaluate its utility in clinical diagnosis and management of patients with autoimmune thyroid disease. Here we describe the procedure ultimately adopted, its major properties, and the res...

AIMS To study the feasibility of a new semiautomatic echocardiographic modality called Tissue Synchronization Imaging (TSI) for measurement of the longitudinal left ventricular (LV) movement. METHODS AND RESULTS TSI was used in 20 subjects with structurally normal hearts to measure the time aspect of the regional longitudinal LV systolic movement in the apical four chamber view. Inter- and in...

BACKGROUND The transient symptoms with lacunar infarction (TSI) and persistent symptoms with lacunar infarction (PSI) are the most common forms of symptomatic lacunar infarction (LI). The aim of this study was to compare the differences in TSI and PSI of symptomatic LI. METHODS A prospective cohort study was conducted in the neurologic outpatients of the tertiary teaching hospital in Northern...

Imagery is often used to accomplish some computational task. In such cases there are some aspects of the imagery that are relevant to the task and other aspects that are not. In order to quantify the task-specific quality of such imagery, we introduce the concept of task-specific information (TSI). A formal framework for the computation of TSI is described and is applied to three common tasks: ...

BACKGROUND/AIMS Graves' disease (GD) is caused by thyroid-stimulating hormone receptor (TSHR) and thyroid-stimulating immunoglobulin (TSI). We used a recently introduced, technically enhanced TSI bioassay to assess its diagnostic value and determine the cut-off in patients in high iodine intake area. METHODS In a cross-sectional setting, we collected serum from 67 patients with untreated GD, ...