Background: Our purpose was to investigate propolis and its component caffeic acid phenethyl ester (CAPE) for their antioxidant effects on the brain tissue of rats exposed to ionizing radiation (IR). Materials and Methods: Fifty-four male albino Sprague-Dawley rats, divided into six groups, were designed as normal control group, cranial irradiation of 5 Gray alone, irradiation plus CAPE, irradi...

objective(s): pulmonary fibrosis (pf) is the most common outcome of a collection of diverse lung disorders known as interstitial lung diseases. it is proposed that alterations in the levels of fibrogenic mediators and the profibrotic/antifibrotic imbalance play a substantial role in the progression of pf in animal models and possibly in humans. caffeic acid phenethyl ester (cape), an active com...

treatment with amiodarone, a commonly prescribed antidysrhythmic agent, is associated with pulmonary fibrosis (pf) which is a commonly progressive and untreatable dieases. caffeic acid phenethyl ester (cape) is a phenolic antioxidant and an active anti-inflammatory, anticancer, antimicrobial and antioxidant component of propolis (bee glue; a resinous hive product collected by honey bees). in th...

Address: Director, Bioethics Centre, Department of Medicine, University of Cape Town, Observatory 7925, Western Cape, South Africa, The Husein Lalji Dewraj Professor of Paediatrics & Child Health, Department of Paediatrics, The Aga Khan University, Karachi, Pakistan, Director, Program on Applied Ethics and Biotechnology, Professor of Public Health Sciences and Surgery, University of Toronto Joi...

idiopathic pulmonary fibrosis (ipf) is a chronic lung disease of unknown etiology. recent investigations have demonstrated that the impaired immune response is a common characteristic feature of ipf. unfortunately, no definitive and effective drug treatment is available that could improve or at least inhibit the progressive course of this fatal disease. that is why one of the main priorities of...

background: our purpose was to investigate propolis and its component caffeic acid phenethyl ester (cape) for their antioxidant effects on the brain tissue of rats exposed to ionizing radiation (ir). materials and methods: fifty-four male albino sprague-dawley rats, divided into six groups, were designed as normal control group, cranial irradiation of 5 gray alone, irradiation plus cape, irradi...

Faculdade de Medicina, Universidade Eduardo Mondlane, Maputo, Mozambique; Duke University Medical Center, Durham, North Carolina; Cardiology Unit, Department of Internal Medicine, Cardiology Unit, Faculty of Medicine and Biomedical ciences, University of Yaoundé I, Yaoundé, Cameroon; Soweto Cardiovascular Research Unit, Department of Cardiology, Chris Hani Baragwanath Hospital, niversity of the...

The present investigation of shallow-water gastropod Bulinus globosus is reported on nearshore sites in and around Cape Maclear on the northwestern part of the Nankumba Peninsula, Lake Malawi (part of Lake Malawi National Park) at a depth of 10 M. The present remark focuses on the geographical distribution and habitats of this group and sample have observed in Cape Maclear Island, Republic of M...

The importance of rainfall to a cavity-nesting species A.N. Radford & M.A. Du Plessis The importance of rainfall to a cavity-nesting species ANDREW N. RADFORD 1 * & MORNÉ A. DU PLESSIS 2 1 Department of Zoology, University of Cambridge, Downing Street, Cambridge CB2 3EJ, UK 2 Percy FitzPatrick Institute of African Ornithology, Department of Zoology, University of Cape Town, Rondebosch 7701, Cap...