This case examines the business development and strategic expansion of Greenway Medical Technologies, a software company delivering electronic healthcare solutions to physicians operating small practices. Over a period of seven years and with an investment of $70 million, Greenway built a best-in-class software application. The case also describes the electronic medical record systems industry ...

I t has recently been observed that many weeks after injection of small amounts of antigen, removal of ant ibody from the circulation results in a specific, secondary-type, ant ibody response (1, 2). This observation suggests that a dynamic equilibrium between persisting immunogen and circulating antibody regulates the immune response (3), and further, that immunocompetent cells can capture ant...

Icariin is recognized as the major bioactive component of Herba Epimedii. The aim of this study was to evaluate the anti-fatigue properties of icariin using a weight-loaded forced swimming test. The mice were randomly divided into four groups, a control group and three icariin treatment groups. The icariin treated groups received different doses of icariin per os (100, 200 and 400 mg/kg of body...

Vastus medialis muscle of a 52-year-old male professional weight-lifter (master degree) was ruptured during training. After 3 days, he (HG.,D. Height: 179 cm, Weight: 98 kg) was admitted to sports medicine clinic with oedema, pain, and swelling on the medial side of his right knee (dominant side). After the physical examination and MRI assessment, nearly total vastus medialis rupture was detect...

The level of stem cell proliferation must be tightly controlled for proper development and tissue homeostasis. Multiple levels of gene regulation are often employed to regulate stem cell proliferation to ensure that the amount of proliferation is aligned with the needs of the tissue. Herewe focus on proteasome-mediated protein degradation as ameansof regulating the activities of proteins involv...

Study Objective: To examine whether differences in patterns of brain activation under baseline conditions relate to the differences in sleepdeprivation vulnerability. Design: Using blood oxygenation level dependent (BOLD) functional magnetic resonance imaging, we scanned 33 healthy young men while they performed the Sternberg working memory task following a normal night of sleep and again follo...

UK forests and woodlands are often of considerable value to biodiversity. There is now a growing need to evaluate the impacts of forest management on biodiversity, in order to maintain and enhance the wildlife value at the landscape scale. The development of biodiversity evaluation tools will enable forest and land managers to make informed choices at this scale in order to provide sustainable ...

"For the respect his works have commanded of musicians, and the popularity they have enjoyed among wider audiences, he is probably the most admired composer in the history of Western music." With this appraisal the New Grove Dictionary of Music and Musicians, published in 1980, begins its magisterial article on Beethoven. More than a decade later one might not apply this statement to the Teuton...