نتایج جستجو برای: سنسورهای رطوبتی tdr
تعداد نتایج: 5259 فیلتر نتایج به سال:
The pathways for the formation of DNA-thymine from syn thesis de novo and from exogenous thymidine (TdR) have been studied in intact leukocytes from patients with chronic myelogenous leukemia. The most significant observations were as follows: (a) DNA-thymine derived from exogenous TdR in creases from 13% to 87% over a range of TdR concentrations from 0.03 /¿Mto 300 /XM.(b) TdR causes expansio...
HIV-1 transmitted drug resistance (TDR) could reverse the gains of antiretroviral rollout. To ensure that current first-line therapies remain effective, TDR levels in recently infected treatment-naive patients need to be monitored. A literature review and data mining exercise was carried out to determine the temporal trends in TDR in South Africa. In addition, 72 sequences from seroconvertors i...
To characterize and compare the thymidine (TdR) and deoxycytidine (CdR) kinase isozymes of uninfected and herpesvirus-infected cells: (i) the subcellular distribution of the isozymes has been studied; (ii) a specific assay for CdR kinase has been devised; (iii) the TdR kinase isozymes have been partially purified; and (iv) the purified enzymes have been analyzed by disc polyacrylamide gel elect...
BACKGROUND Human immunodeficiency virus type 1 (HIV-1) transmitted drug resistance (TDR) can compromise antiretroviral therapy (ART) and thus represents an important public health concern. Typically, sources of TDR remain unknown, but they can be characterized with molecular epidemiologic approaches. We used the highly representative Swiss HIV Cohort Study (SHCS) and linked drug resistance data...
We aimed to study epidemic trends and predictors for transmitted drug resistance (TDR) in our region, its clinical impact and its association with transmission clusters. We included 778 patients from the AIDS Reference Center in Leuven (Belgium) diagnosed from 1998 to 2012. Resistance testing was performed using population-based sequencing and TDR was estimated using the WHO-2009 surveillance l...
Recently, we reported the tetrodotoxin (TTX)- and dihydropyridine (DHP)-resistant (TDR) inward currents in neonatal mouse spinal neurons. In this study, we further characterized these currents in the presence of 1-5 μM TTX and 20-30 μM DHP (nifedipine, nimodipine, or isradipine). TDR inward currents were recorded by voltage ramp (persistent inward current, TDR-PIC) and step (TDR-I(p)) protocols...
BACKGROUND Transmission of drug-resistant HIV-1 (TDR) can impair the virologic response to antiretroviral combination therapy. Aim of the study was to assess the impact of TDR on treatment success of resistance test-guided first-line therapy in the German HIV-1 Seroconverter Cohort for patients infected with HIV between 1996 and 2010. An update of the prevalence of TDR and trend over time was p...
Rapid movement of agricultural chemicals through soil to groundwater via preferential flow pathways is one cause of water contamination. Previous studies have shown that time domain reflectometry (TDR) could be used to characterize solute transport in soil. However, previous studies have only scarcely addressed preferential flow. This study presents an extended application of TDR for determinin...
DNA biosynthesis in monkey kidney and LM cell cultures. The thymidine (TdR) kinase activities of green monkey kidney (GMK or CV-1) and HeLa, but not LM or LM(TK~), cell cultures were greatly increased after ara-C treatment. A smaller increase of deoxycytidylic (dCMP) deaminase, but not of the thymidylic (TMP) kinase activity, was also found. The induction of TdR kinase activity by ara-C was pre...
OBJECTIVES To describe current practice in testing for transmitted antiretroviral drug resistance (TDR) and the prevalence of TDR in a large UK HIV-1 cohort. METHODS The study includes a retrospective analysis of newly diagnosed HIV-1-infected patients presenting to eight HIV clinics in the north of England between March 2005 and March 2007. Resistance mutations were defined by IAS-USA. Predi...
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