................................................................................................. 7 LIST OF ORIGINAL PUBLICATIONS...................................................... 9 INTRODUCTION ...................................................................................... 10 REVIEW OF THE LITERATURE ............................................................ 11 Definition and clin...

OBJECTIVES To investigate whether cerebral, liver, and infraumbilical regional tissue oxygen saturation (rSO2) and fractional tissue oxygen extraction (FTOE) could be used to diagnose necrotizing enterocolitis (NEC) and complicated NEC (Bell's stage 3B or death) during its early stages. METHODS A prospective observational cohort study of preterm infants with suspected or diagnosed NEC. We com...

Purpose: The purpose of this study was to examine the usefulness of abdominal sonography in the diagnosis of necrotizing enterocolitis (NEC). Methods: We reviewed the medical records of 51 neonates who were diagnosed with NEC in the neonatal intensive care unit at Yeouido St. Mary’s Hospital of the Catholic University in Korea between January 2008 and December 2012. The neonates under­ went abd...

nec is inflammatory necrosis of intestine with most common site being terminal ileum and ascending colon in preterm babies (1). the condition is typically seen in premature infants, and the timing of its onset is generally inversely proportional to the gestational age of the baby at birth, i.e. the earlier a baby is born, longer is the time of risk for nec in premature babies. the incidence of ...

This report summarizes the work done at NEC Labs America, Princeton from 28th May 2008 to 29th August 2008. I worked under the supervision of Martin Roetteler and collaborated with Hari Krovi. We worked on the hidden subgroup problem(HSP) for dihedral group. Dihedral HSP will solve f(n)-shortest vector lattice problem for f(n) = n 1 2 ([1]), which imply connection with some cryptographic protoc...

PURPOSE To investigate the association between necrotizing enterocolitis (NEC) and red blood cell transfusions in very low birth weight (VLBW) preterm infants. METHODS We studied were 180 VLBW preterm infants who were admitted to the neonatal intensive care unit of CHA Gangnam Hospital from January of 2006 to December of 2009. The subjects were divided into 2 groups: an NEC group (greater tha...

Purpose: To investigate the association between necrotizing enterocolitis (NEC) and red blood cell transfusions in very low birth weight (VLBW) preterm infants. Methods: We studied were 180 VLBW preterm infants who were admitted to the neonatal intensive care unit of CHA Gangnam Hospital from January of 2006 to December of 2009. The subjects were divided into 2 groups: an NEC group (greater tha...

Background: Necrotizing enterocolitis is one of the serious complications of prematurity. Eosinophilia has not been proposed as a classical laboratory abnormality in NEC. Previous studies suggest that eosinophilia during NEC may be a sign of allergic enterocolitis. Case presentation: We present a premature neonate with birth weight of 1280 grams with abdominal distention, bilious gastric resid...

BACKGROUND Endoplasmic reticulum (ER) stress and activation of the unfolded protein response (UPR) play important roles in chronic intestinal inflammation. Necrotizing enterocolitis (NEC) is the most common gastrointestinal emergency in preterm infants and is characterized by acute intestinal inflammation and necrosis. The objective of the study is to investigate the role of ER stress and the U...

To identify early markers of necrotizing enterocolitis (NEC), we hypothesized that continuous abdominal near-infrared spectroscopy (A-NIRS) measurement of splanchnic tissue oxygen saturation and intermittent plasma intestinal fatty-acid binding protein (pI-FABP) measured every 6 hours can detect NEC prior to onset of clinical symptoms. Premature piglets received parenteral nutrition for 48-hour...