Introduction: This research was a retrospective study on the prevalence of nosocomial infections (NIs) and the associated risk factors among the patients admitted to the surgery and internal Intensive Care Units (ICU). Materials and Methods: This cross-sectional descriptive study was conducted on patients admitted to ICUs over one year. Clinical data of patients, including demographic informat...

UNLABELLED The Na(+)/I(-) symporter (NIS) has been proposed as an imaging reporter gene to ascertain the expression of therapeutic genes in targeted tissues. In this study, we investigated whether posttranslational processing and cell-surface trafficking of NIS affect NIS-mediated radioiodide uptake in cells expressing exogenous NIS. METHODS We established FTC133, HeLa, and PC12 cell lines wi...

UNLABELLED The sodium (Na+)/iodide (I-)-symporter (NIS) is abundantly expressed and accumulates iodide in thyroid follicular cells. The NIS is also found in extrathyroidal tissues, particularly gastric mucosa. Controversies exist on the localization of extrathyroidal NIS. We have studied the presence of both NIS peptide and NIS messenger RNA (mRNA) in the digestive tract and thyroid from differ...

conclusions the frequency of nis in this hospital was lower in comparison with other worldwide studies. however, low incidence of health care-associated infections in our study may be due to under diagnosis and underreporting of such infections by health care staff. results the incidence of nis was low (i.e. < 2%). among 16936 admitted patients in this hospital, 174 patients (79 males and 95 fe...

The sodium (Na)/iodide (I)-symporter (NIS) is abundantly expressed and accumulates iodide in thyroid follicular cells. The NIS is also found in extrathyroidal tissues, particularly gastric mucosa. Controversies exist on the localization of extrathyroidal NIS. We have studied the presence of both NIS peptide and NIS messenger RNA (mRNA) in the digestive tract and thyroid from different mammals. ...

A. Generation of anti-NIS antibodies 1086 B. N-linked glycosylation of NIS: implications for the NIS secondary structure model 1087 C. Extracellular orientation of the NH 2 terminus of NIS 1087 D. Several hydroxyl-containing amino acid residues in the transmembrane segment IX (Ser-353, Thr-354, Ser-356, and Thr-357) are important for NIS function 1088 E. Electrophysiological analysis of NIS: me...

Received 4/21/2003; revised 05/23/2003; accepted 5/30/2003. For correspondence or reprints contact: Wen-Sheng Huang, M.D., Department of Nuclear Medicine, Tri-Service General Hospital, 325, Section 2, Cheng-Kung Road, Taipei, Taiwan, R.O.C. Tel: (886)2-87927216, Fax: (886)2-87927217, E-mail: [email protected] The Na/I symporter (NIS) is the membrane protein mediating iodide translocation ...

Background. Pediatric patients with neoplastic diseases are more likely to develop nosocomial infections (NIs). NIs may prolong their hospital stay, and increase morbidity and mortality. Objectives. The objectives of this study were to determine: (1) the incidence of NIs, (2) sites of NIs, (3) causal organisms, and (4) outcomes of NIs among pediatric patients with neoplastic diseases. Methods. ...

Cold thyroid nodules (CTNs) are characterized by a reduced iodide uptake in comparison to normal thyroid tissue. The sodium iodide symporter (NIS) is the first step in thyroid hormone synthesis and mediates the active iodide transport in the thyroid cells suggesting that decreased iodide uptake could be a result of changes in NIS expression or molecular defects in the NIS gene. In contrast to p...