The three Caenorhabditis elegans beta-catenin each function in distinct processes: BAR-1 in canonical Wnt signaling that controls cell fates and cell migrations, HMP-2 in cell adhesion and WRM-1 in Wnt signaling pathways that function in conjunction with a mitogen-activated kinase (MAPK) pathway to control the orientations, or cell polarities, of cells that undergo asymmetric cell divisions. In...

Historically, pasture breeders have not considered environmental weed risk in species selection and assessment. Consequently several pasture or former pasture species are now problematic environmental weeds in Australia. The CRC for Plant-Based Management of Dryland Salinity (CRC) has taken a pro-active approach to prevent further introduction or promotion of weedy pasture species by developing...

The APC tumor suppressor regulates diverse stem cell processes including gene regulation through Wnt-β-catenin signaling and chromosome stability through microtubule interactions, but how the disparate functions of APC are controlled is not well understood. Acting as part of a Wnt-β-catenin pathway that controls asymmetric cell division, Caenorhabditis elegans APC, APR-1, promotes asymmetric nu...

A method for deriving quantitative relationships between road slipperiness, traffic accident risk and winter road maintenance (WRM) activity is described. The method is also applied to data from an area in southern Sweden. If a specific type of road slipperiness represents a large accident risk despite high WRM activity it is important to increase public awareness during such periods. If the ty...

During C. elegans development, Wnt/WG signaling is required for differences in cell fate between sister cells born from anterior/posterior divisions. A beta-catenin-related gene, wrm-1, and the lit-1 gene are effectors of this signaling pathway and appear to downregulate the activity of POP-1, a TCF/LEF-related protein, in posterior daughter cells. We show here that lit-1 encodes a serine/threo...

-Catenin regulates cell adhesion and cellular differentiation during development, and misregulation of -catenin contributes to numerous forms of cancer in humans. Here we describe Caenorhabditis elegans conditional alleles of mom-2/Wnt, mom-4/Tak1, and wrm1/ -catenin. We use these reagents to examine the regulation of WRM-1/ -catenin during a Wnt-signaling-induced asymmetric cell division. Whil...

1 regulate cortical release of WRM-1/beta-catenin to control cell division orientation in early Caenorhabditis elegans embryos"

In accordance with the rapid proliferation of machine learning (ML) and data management, ML applications have evolved to encompass all engineering disciplines. Owing importance world’s water supply throughout rest this century, much research has been concentrated on application strategies integrated resources management (WRM). Thus, a thorough well-organized review that is required. To accommod...

The APC tumor suppressor regulates diverse stem cell processes including gene regulation through Wnt–b-catenin signaling and chromosome stability through microtubule interactions, but how the disparate functions of APC are controlled is not well understood. Acting as part of a Wnt–b-catenin pathway that controls asymmetric cell division, Caenorhabditis elegans APC, APR-1, promotes asymmetric nu...

beta-Catenins function both in cell adhesion as part of the cadherin/catenin complex and in Wnt signal transduction as transcription factors. Vertebrates express two related proteins, beta-catenin and plakoglobin, while Drosophila has a single family member, Armadillo. Caenorhabditis elegans expresses three beta-catenin-related proteins, BAR-1, HMP-2, and WRM-1, which are quite diverged in sequ...