OBJECTIVES This study was aimed to examine the anti-epileptic activity of leaf extracts of Punica granatum in experimental models of epilepsy in Swiss albino mice. MATERIALS AND METHODS Petroleum ether leaf extract of P. granatum (PLPG), methanolic LPG (MLPG), and aqueous LPG (ALPG) extracts of P. granatum leaves was initially evaluated against 6-Hz-induced seizure model; the potent extract w...

A non-compactly supported cubic radial basis function implementation of the MLPG method for beam problems is presented. The evaluation of the derivatives of the shape functions obtained from the radial basis function interpolation is much simpler than the evaluation of the moving least squares shape function derivatives. The radial basis MLPG yields results as accurate or better than those obta...

This paper presents the implementation of a three-dimensional dynamic code, for contact, impact, and penetration mechanics, based on the Meshless Local Petrov-Galerkin (MLPG) approach. In the current implementation, both velocities and velocity-gradients are interpolated independently, and their compatibility is enforced only at nodal points. As a result, the time consuming differentiations of ...

Abstract In this research, a simulation–optimization (S/O) model is used in order to estimate aquifer parameters on two aquifers. model, meshless local Petrov–Galerkin (MLPG) for simulation purpose and modified teaching–learning-based optimization (MTLBO) algorithm engaged as model. Linking these powerful models generates S/O named MLPG-MTLBO. The proposed applied aquifers: standard real field ...

The truly Meshless Local Petrov-Galerkin (MLPG) method is extended to solve the incompressible Navier-Stokes equations. The local weak form is modified in a very careful way so as to ovecome the so-called Babus̃ka-Brezzi conditions. In addition, The upwinding scheme as developed in Lin and Atluri (2000a) and Lin and Atluri (2000b) is used to stabilize the convection operator in the streamline di...

Protozoan parasites of the genus Leishmania cause a number of important human diseases. One of the key determinants of parasite infectivity and survival is the surface glycoconjugate lipophosphoglycan (LPG). In addition, LPG is shown to be useful as a transmission blocking vaccine. Since culture supernatant of parasite promastigotes is a good source of LPG, we made attempts to characterize func...

A comparison study of the efficiency and accuracy of a variety of meshless trial and test functions is presented in this paper, based on the general concept of the meshless local Petrov-Galerkin (MLPG) method. 5 types of trial functions, and 6 types of test functions are explored. Different test functions result in different MLPG methods, and six such MLPG methods are presented in this paper. I...

Recently, the efficiency of computer modeling and simulations has been improving dramatically. Consequently, the structural analysis of welding phenomena based on thermaleelasticeplastic finite element method (FEM) can be performedwith a good accuracy in a short time. However, if themodel to be analyzed is large and it has a complex shape, problemsmight occur with preprocessing, such as themesh...

The Meshless Local Petrov-Galerkin (MLPG) “mixed collocation” method is applied to the problem of topology-optimization of elastic structures. In this paper, the topic of compliance minimization of elastic structures is pursued, and nodal design variables which represent nodal volume fractions at discretized nodes are adopted. A so-called nodal sensitivity filter is employed, to prevent the phe...