Sixty years ago, musique concrète was born of the singlehanded efforts of one man, Pierre Schaeffer. How did the first experiments become a School and produce so many rich works? As this issue of Organised Sound addresses various aspects of the GRM activities throughout sixty years of musical adventure, this article discusses the musical thoughts behind the advent and the development of the mus...

Existing treatment maneuvers for posterior canal benign paroxysmal positional vertigo (PC-BPPV) include the Semont liberatory maneuver (SLM) and canalith repositioning maneuver (CRM). Independent investigations reveal that these maneuvers provide an excellent outcome for most patients. However, certain aspects of these maneuvers, such as hyperextension of the neck for CRM and brisk lateral moti...

Cytotoxic lymphocyte protease GrM (granzyme M) is a potent inducer of tumour cell death and a key regulator of inflammation. Although hGrM (human GrM) and mGrM (mouse GrM) display extensive sequence homology, the substrate specificity of mGrM remains unknown. In the present study, we show that hGrM and mGrM have diverged during evolution. Positional scanning libraries of tetrapeptide substrates...

Reverse shoulder arthroplasty may be performed using components that medialize or lateralize the center of rotation. The purpose of this prospective study was to directly compare 2 reverse shoulder arthroplasty designs. Two treatment groups and 1 control group were identified. Group I comprised 9 patients using a medialized Grammont-style (GRM) prosthesis with a neck-shaft angle of 155°. Group ...

The main feature of global repeat map (GRM) algorithm (www.hazu.hr/grm/software/win/grm2012.exe) is its ability to identify a broad variety of repeats of unbounded length that can be arbitrarily distant in sequences as large as human chromosomes. The efficacy is due to the use of complete set of a K-string ensemble which enables a new method of direct mapping of symbolic DNA sequence into frequ...

An efficient and systematic methodology for the kinematic analysis of geared robot Ž . manipulators GRMs with a jointed unit is presented. It is shown that, by decomposing mechanical transmission lines of a GRM into serially connected jointed and disjointed units, kinematic relation between local inputs and local outputs of admissible jointed units can be systematically formulated. Accordingly,...

Brains and sensory systems evolved to guide motion. Central to this task is controlling the approach to stationary obstacles and detecting moving organisms. Looming has been proposed as the main monocular visual cue for detecting the approach of other animals and avoiding collisions with stationary obstacles. Elegant neural mechanisms for looming detection have been found in the brain of insect...

Linear relation is valuable in rule discovery of stocks, such as ”if stock X goes up 1, stock Y will go down 3”, etc. The traditional linear regression models the linear relation of two sequences perfectly. However, if user asks ”please cluster the stocks in the NASDAQ market into groups where sequences have strong linear relationship with each other”, it is prohibitively expensive to compare s...

abstract background: the increase in breast cancer incidence has enhanced attention towards breast cancer risk. the aim of this study was to determine the risk of breast cancer and risk perception of women, factors that affect risk perception, and to determine differences between absolute risk and the perception of risk. methods: this cross-sectional study was carried out among 346 women whose ...

SODIUM soneryl, the sodium salt of butyl ethyl barbituric acid, is-olle of the least toxic of the barbiturates. In the series of cases under considleration, consisting of routine general surgical cases, it has, on the whole, given excellent results. Larger doses are tolerated than in the case of most of the other barbiturates, and the ratio between the medicinal and the lethal dose is high. Aft...