BACKGROUND Data regarding the prevalence of chronic spontaneous urticaria (CSU) in childhood-onset systemic lupus erythematosus (cSLE) patients and possible associated factors are limited to a few case reports. The objectives of this study were to assess CSU in a large cSLE population, in order to evaluate the demographic data, clinical manifestations, disease activity/damage, laboratory abnorm...

Effective coalition operations require support for dynamic information gathering, processing, and sharing at the network edge for Collective Situation Understanding (CSU). To enhance CSU and leverage the combined strengths of humans and machines, we propose a conversational interface using Controlled Natural Language (CNL), which is both human readable and machine processable, for shared inform...

BACKGROUND Chronic spontaneous urticaria (CSU) is associated with activation of acute phase response. On the other hand, it is known that systemic inflammation may lead to increased formation of advanced glycation end-products (AGEs), associated with pathogenesis of various diseases. AIM We aim to test whether chronic inflammation manifested by activated acute phase response may provide a mec...

BACKGROUND Chronic spontaneous urticaria (CSU) formerly known as chronic idiopathic urticaria (CIU) is a severe and distressing skin condition that remains uncontrolled in approximately one half of patients, despite the use of licensed, recommended doses of modern, second-generation H1-antihistamines. So far, the humanistic, societal and economic burden of CSU/CIU has not been well quantified. ...

BACKGROUND Chronic spontaneous urticaria (csU), which is characterized by recurrent episodes of mast cell-driven wheal and flare-type skin reactions, is often associated with elevated total IgE levels and thyroid autoimmunity. We speculate that some csU patients express IgE autoantibodies against thyroid antigens such as thyroid peroxidase (TPO), which could bind to skin mast cells and induce t...

clock .. . . . primary data/control inputs .. parallel scan data input primary data outputs Figure 4.7.: CSU-accurate FSM representation of a reconfigurable scan network a full CSU operation, i.e., multiple clock cycles in the cycle-accurate RSN model. An example is given in Figure 4.6 where k cycles of a CSU operation are combined into a single transition in the CAM. The block diagram of a CSU...

OBJECTIVE To assess the clinical status of chronic spontaneous urticaria (CSU) and understand treatment approaches in Italy through specialists who treat CSU (dermatologists and allergy specialists) and CSU patients' experience. DESIGN Multicentre survey. SETTING Online structured questionnaires (one for physicians and one for patients). PARTICIPANTS Physicians and patients with CSU in It...

Chronic idiopathic/spontaneous urticaria (CIU/CSU), which affects ~1% of the United States population, is defined as recurrent hives for >6 weeks (Kaplan and Greaves, 2009). Active CIU/CSU patients uniquely display suppressed basophil FcεRI-mediated histamine release (BHR) (Saini, 2014). This is a feature that improves in disease remission (Eckman et al., 2008; Kern and Lichtenstein, 1976; Oliv...

INTRODUCTION Few studies have described chronic idiopathic/spontaneous urticaria (CIU/CSU) healthcare burden in adults, while this information remains largely unknown in children. We aimed to describe treatment patterns, healthcare resource utilization (HRU), and costs in CIU/CSU pediatric patients, as well as to compare HRU and costs in CIU/CSU and CIU/CSU-free pediatric patients. METHODS Me...

1.1 Sorting Code: 2001–STAR–D1; responding to Statistical Research Area 2 1.2 Title: Project 1: Combining Environmental Data Sets 1.3 Investigators: Jennifer A. Hoeting (Principal Investigator, CSU), Richard A. Davis (CSU), F. Jay Breidt (CSU), Robin Reich (CSU), Don L. Stevens, Jr (OSU), and Steven B. Weisberg (SCCWRP). 1.4 Institution: Colorado State University, Oregon State University, and S...