Cartilage matrix protein (CMP) is a major component of the extracellular matrix of nonarticular cartilage. The structure and chromosomal location of the human gene encoding CMP was determined by molecular cloning analysis. We used a partial chicken CMP cDNA probe to isolate three overlapping human genomic clones. From one of these clones, a probe containing 2 human CMP exons was isolated and us...

Cardiomyopathy (CMP) is a heterogeneous disease caused by a functional abnormality of the cardiac muscle. CMP is of 2 major types, dilated and hypertrophic, and is further classified as either primary or secondary. Secondary CMP is caused by extrinsic factors, including infection, ischemia, hypertension, and metabolic disorders. Primary CMP is diagnosed when the extrinsic factors of secondary C...

Cartilage matrix protein (CMP) is the prototype of the newly discovered matrilin family, all of which contain von Willebrand factor A domains. Although the function of matrilins remain unclear, we have shown that, in primary chondrocyte cultures, CMP (matrilin-1) forms a filamentous network, which is made up of two types of filaments, a collagen-dependent one and a collagen-independent one. In ...

BACKGROUND Previous studies have reported worse outcomes in children with nondilated cardiomyopathy (CMP) listed for heart transplant compared with children with dilated CMP. We sought to compare wait-list and posttransplant outcomes in these groups in the current era. METHODS AND RESULTS We analyzed all children <18 years of age with a diagnosis of CMP listed for heart transplant in the Unit...

BACKGROUND Cardiac amyloidosis due to amyloid fibril deposition in the heart results in cardiomyopathy (CMP) with heart failure (HF) and/or conduction disturbances. Immunoglobulin light chain-related CMP (AL-CMP) features rapidly progressive HF with an extremely poor prognosis compared with a CMP due to the deposition of mutant (ATTR) amyloidosis or wild-type (senile systemic amyloidosis, SSA) ...

CMP is a planarization technique for multilevel VLSI metallization processes. CMP fills are inserted as a design for manufacturability (DFM) methodology to improve pattern-dependent post-CMP topography, i.e., to improve interconnect planarity. Design-driven fill synthesis seeks to optimize CMP fill with respect to objectives beyond mere density uniformity. Design-driven fill synthesis minimizes...

OBJECTIVE To assess current studies on the relationship between cell-derived microparticles (cMP) and recurrent miscarriages (RM) and pre-eclampsia (PE), and review the relationships between cMP and inflammatory and clot pathways, antiphospholipid antibodies (aPL), cytokines, and pregnancy complications. DESIGN Systematic and comprehensive review of the literature from January 2000 to January...

In this study, a self-designed simultaneous crossflow electrocoagulation/electrofiltration (EC/EF) treatment module was evaluated for its overall reatment performance by treating chemical mechanical polishing (CMP) wastewaters including Cu-CMP wastewater and oxide-CMP wastewater. he critical electric field strengths for Cu-CMP and oxide-CMP wastewaters were determined to be 35 and 30 V/cm, resp...

This work studies the effect of 3-D Chip Multiprocessor (CMP) integration on Amdahl’s law. The influence of vertical communication and thermal gradients on CMP performance and scalability is studied from Amdahl’s law perspective. We find that a fast vertical connectivity enabled by 3-D implementation shifts the optimum CMP configuration towards the larger number of lighter cores, thus improving...

Chip-level CMP modeling is investigated to obtain the post-CMP film profile thickness across a die from its design layout file and a few film deposition and CMP parameters. The work covers both HDP and conformal CVD film. The experimental CMP results agree well with the modeled results. Different algorithms for filling of dummy structure are compared. A “smart” algorithm for dummy filling is pr...