The Cullin2-type ubiquitin ligases belong to the Cullin-Ring Ligase (CRL) family, which is a crucial determinant of proteasome-based degradation processes in eukaryotes. Because of the finding of von Hippel-Lindau tumor suppressor (VHL), the Cullin2-type ubiquitin ligases gain focusing in the research of many diseases, especially in tumors. These multisubunit enzymes are composed of the Ring fi...

در مطالعات زمین‌شناسی و کانی‌شناسی، وجود پوشش‌ گیاهی سالم خشک پیکسل‌های حاوی اطلاعات طیفی اجتناب‌ناپذیر است. بنابراین، بازیابی حد زیرپیکسل، مانند برآورد میزان حضور یک کانی پیکسل از تصاویر سنجش دور ابرطیفی، مسئله‌ای مهم محسوب می‌شود. این پژوهش، روش عمق پیوستار اصلاح‌شدة اثر پوشش (VCCD)، برای کاهش تخمین کانی‌های هدف، با استفاده داده‌های طیف‌سنجی، آزمایشگاهی کانی‌شناسی هایپریون (Hyperion) اصلاح من...

Sustainable construction has gained increasing popularity within the building sector with many sustainability rating systems (SRSs) available worldwide. However, most research been focused on environmental benefits of pursuing SRSs, little attention paid to health and safety (H&S) impact workers. This study thus aims investigate adopting SRSs H&S workers in projects. A systematic litera...

BACKGROUND Psoriasis exerts significant, negative, impact on patients' quality of life (QOL). Recently, the relationship between QOL and skin lesion improvement has been emphasized in the treatment of psoriasis patients. OBJECTIVE The purpose of study was to compare the QOL in psoriasis and other skin diseases, and to evaluate the generic QOL, skin specific QOL, stress, depression and anxiety...

Engaging Postgraduate Students Undertaking Clinical Pharmacology Using GoSoapBox for Problem-Based Learning Engaging student cohorts in the classroom using teacher-centered learning approaches can be difficult (O’Donoghue, Jardine, & Rubner, 2010). Web-based student response systems (SRSs) used by students in the classroom can provide support for student participation in the class and enable an...

هدف: هدف پژوهش حاضر، بررسی و تبین مهارت‏های مورد نیاز مدیران دوره آموزش عمومی در رهبری مدارس دوران کرونا پساکرونا با توجه به تحولات ایجاد شده اثر این بحران است.مواد روش‏ها: از نظر کاربردی روش، کیفی نوع سنتزپژوهی است. قلمرو اصلی‏ترین منابع گردآوری داده‏ها، پژوهش‏های متعددی است که ارتباط مدرسه مجازی داخل خارج ایران انجام متناسب موضوعی پس رعایت ملاک‏های ورود خروج تعداد 47 نمونه انتخاب شدند. مراحل ...

Requirements specifications describe multiple technical concerns of a system and are used throughout the project life-cycle to help sharing a system’s common understanding among multiple stakeholders. The interest to support the definition and the management of system requirements specifications (SRSs) is evident by the diversity of many generic and RE-specific tools. However, little work has b...

This paper presents upper bounds for the Satellite Revenue Selection and Scheduling problem (SRSS). A compact model of this generalized Prize Collecting Traveling Salesman Problem with Time Windows is defined and enriched with valid inequalities based on task interval reasoning. The non-concavity of the objective function to be maximized is also studied. Finally a Russian Dolls approach combine...

Toxoplasma gondii is one of the most successful protozoan parasites of warm-blooded animals. Stage-specific expression of its surface molecules is thought to be key to its ability to establish chronic infection in immunocompetent animals. The rapidly dividing tachyzoite stage displays a different subset of family of surface antigen 1 (SAG1)-related sequences (SRSs) from that displayed by the en...