Gum Guggul (Commiphora mukul), Blue Flag root (Iris versicolor) and seaweeds such as Bladderwrack (Fucus vesiculosus) are naturally occurring compounds that may aid in the treatment of hypothyroidism. Because these work via different mechanisms, they may be combined to synergistically support the thyroidparticularly in situations of thyroid hypofunction and Hashimoto’s Disease. Fucus provides ...

There is accumulating evidence that LDL oxidation is essential for atherogenesis, and that antioxidants that prevent this oxidation may either slow down or prevent atherogenesis. In the present study, we found that Commiphora mukul and its cholesterol-lowering component, guggulsterone, effectively inhibited LDL oxidation mediated by either catalytic copper ions, free radicals generated with the...

This communication deals with the detailed pharmacognostical aspects of commiphora mukul leaves which include morphological and anatomical characters and preliminary phytochemical analysis of the leaves. The microscopical characters of leaf powder are also reported with its salient features. The fluorescent behaviour of powdered drugs with some chemical reagents is also examined.

materials and methods thirty-two adult male wistar rats were randomly allocated to four groups: normal, diabetic, normal + extract of c. mukul and diabetic + extract of c. mukul groups with free access to regular rat diet. diabetes was induced in male rats by single interaperitoneal injection of 60 mg/kg stz. after the confirmation of diabetes, 300 mg/kg c. mukul extract was orally administered...

Breast engorgement is a common problem during breastfeeding that can lead to early discontinuation of breastfeeding. Commiphora Mukul (C. Mukul) is a medicinal plant with analgesic and anti-inflammatory compounds. The present study was conducted to determine the effect of C. Mukul on improving breast engorgement in breastfeeding women. This study was a double-blind, randomized, and placebo-cont...

Guggulu (Commiphora mukul) is about 2-3.5 mt heighted plant of Burceraceae family. The plant grows wild in the arid, rocky tracts, also in low rainy and hot areas. The part used in medicinal preparation is resin, collected by tapping the barks. Guggulu deserves high values in Ayurvedic medicines. Guggulu is Rasayana, Vatakaphaghna, and used in various diseases. Due to high values and excessive ...

OBJECTIVE To report a case of rhabdomyolysis caused by Commiphora mukul, a natural lipid-lowering agent. CASE SUMMARY A 55-year-old man was taking an extract of C. mukul 300 mg 3 times daily to lower his cholesterol level. He developed rhabdomyolysis with hemoglobinuria after 2 weeks of treatment. Laboratory tests showed creatine kinase 144600 IU/L (reference range 24-195), myoglobin >3000 ng...

Alcohollc extract of C. mulnd resin (guggal) and one pure steroid isolated from this extract, when administered orally at a dose of 25-50 mgjkg body weight, reduced the serum cholesterol level in normal and triton-induced byperUpemlc rats and cholesterol-fed byperlipemIc rabbits. Both guggal extract and the steroid showed only slight inhibition of cholesterol biosynthesIs 85 compared to p_chlor...

Guggulu is an oleo-gum resin which exudes out as a result of injury from the bark of Commiphora wightii (Arnott) Bhandari [syn.  Commiphora mukul (Hook. Ex Stocks) Engl; Balsamodendron mukul (Hook. Ex Stocks); Family, Burseraceae]. It has been used in the Ayurveda since time immemorial for the treatment of variety of disorders such as inflammation, gout, rheumatism, obesity, and disorders of li...

The purpose of this study was to investigate the effects of Commiphora mukul gum resin ethanolic extract (CMEEt) administration against altered activities of key enzymes of carbohydrate metabolism, lipid metabolism and changes in glycogen content (liver and muscle) and lipids (liver and heart) in streptozotocin (STZ) induced insulin deficient diabetic Wistar albino rats. Diabetes was induced by...