background :although the incidence of animal bite is increasing in iran, there is no sufficient knowledge about delayed post-exposure prophylaxis (pep). hence, the aim of this study was to evaluate delayed pep and its associated factors in bitten people.   methods : this cross-sectional study was conducted in tuyserkan district of hamadan province (west of iran) from february 2011 to february 2...

Abstract The tyrosine phosphatase PTPN22 encodes the enzyme Lyp (PEP in mice) all immune cells. 5–10% of North American population expresses autoimmunity risk allele 1858C>T (rs2476601) causing amino acid substitution R620W (R619W mice). This mutation alters lymphocyte activation, toll-like receptor signaling, and cytokine production. Ptpn22 knockout (PEP-null) alternative allele-express...

The aim of this work was to discover the extent of interference by phosphoenolpyruvate (PEP) phosphatase in spectrophotometric assays of PEP carboxylase (EC 4.1.1.31) in crude extracts of plant organs. The presence of PEP phosphatase and lactate dehydrogenase (EC 1.1.1.27) in extracts leads to PEP-dependent NADH oxidation that is independent of PEP carboxylase activity, and hence to overestimat...

Gluten is a protein group found in wheat, barley, rye, and oats, known as cereals. When this vegetable introduced into the body, celiac disease can occurs. The use of bacterial fungal oligopeptidase to ensure cleavage gluten non-toxic fragments are considered promising alternative for disease. In study, Aspergillus niger Prolyl EndoPeptidase (AN-PEP) enzyme was cloned pET22b vector recombinantl...

Traditionally, impedance derived measures of cardiac autonomic balance (CAB) and regulation (CAR) are calculated using indices heart rate variability (HRV) that primarily reflect parasympathetic nervous system activity (e.g., high-frequency HRV | HF-HRV) pre-ejection period (PEP; a systolic time interval measure sympathetic activity). However, HF-HRV PEP considered chronotropic inotropic influe...

OBJECTIVE To assess and compare immediate effects of chest physiotherapy with positive expiratory pressure (PEP) versus oscillating PEP on transcutaneously measured blood-gas tensions in patients with cystic fibrosis. METHODS Fifteen patients (mean age 12.5 y, range 6.9-21.5 y) participated. The treatments were randomized and performed on 2 separate occasions, 8 weeks apart. Spirometry was co...