Scleredema adultorum of Buschke is a rare disorder characterized by diffuse swelling and non-pitting induration of the skin usually involving the face, neck, arms and upper trunk. It has been associated with previous infectious diseases, diabetes, paraproteinemia and, more rarely, malignant neoplasms or autoimmune disorders. We report the case of a 30-year-old man who presented with a 2-year hi...

Since Buschke and Löwenstein first described the giant condyloma in 1925 (which subsequently was named Buschke-Löwenstein tumor), there have been scattered reports over the past 90 years describing presentation and different avenues of treatment for patients with this condition. It is well known that immunocompromised individuals are at an increased risk of anogenital disease caused by human pa...

AIM To recognize a line of treatment for scleredema of Buschke in an adolescent. BACKGROUND Scleredema of Buschke is an uncommon disorder characterized by induration of the skin, which includes a non pitting hardening of the skin around the neck, shoulders, and trunk sometimes the face. Three variants are recognized. The histopathologic features of scleredema are characterized by thickened co...

Cheung Sha Wan Dermatology Clinic, 3/F, West Kowloon Health Centre, 303 Cheung Sha Wan Road, Kowloon, Hong Kong A 59-year-old Chinese male presented with 6 months history of gradual development of thickened skin over nape of neck and back. Another 34-year-old Chinese male had more extensive hardening of skin over nape of neck and then extended to the upper back, shoulder, arms, chest wall, face...

BACKGROUND Giant condyloma acuminatum or Buschke - Loewenstein tumor is a very rare disease usually located in the genital, anorectal, and perianal regions. It is locally invasive but in mostly cases displays a benign cytology on preoperative tissue sampling. Because of its low incidence little is known about treatment outcomes. Complete surgical excision is the treatment of choice. Different s...

Buschke-Löwenstein tumor is a rare manifestation of a sexually transmitted human papilloma virus infection that affects the anogenital area. Wide local excision of the lesion is the mainstay of treatment. Malignancy though must be excluded.

Main text A 46-year-old African-American male with a history of type-1 diabetes (DM) was referred to the Rheumatology clinic for a further evaluation of possible systemic scleroderma. He reported a 3-year history of skin thickening and hyperpigmentation on his back and shoulders. Over the last 12 months, his symptoms progressed, involving the proximal arms, legs, and back with sparing of his ha...