High amounts of time spent sedentary and low levels of physical activity have been implicated in the process of excessive adiposity gains in youth. The aim of this review is to discuss the role of physical activity, sedentary time and behaviour (i.e. television (TV)-viewing) in relation to adiposity during the first two decades of life with a specific focus on whether the association between se...

Eighteen day old neonate presented with features of early neonatal sepsis. History of mother revealed a travel from non-endemic area of malaria to endemic area, and on the 7th gestational age mother detected as having malaria. She was treated with quinine and cured. Baby was also evaluated for congenital malaria in first few neonatal days and discharged. Now the baby on evaluation shows anemia,...

1 Department of Neurology, University Hospital Zurich, 8091 Zurich, Switzerland 2 Division of Neuropsychology, Institute of Psychology, University of Zurich, 8050 Zurich, Switzerland 3 Department of Psychiatry, University Hospital Zurich, 8091 Zurich, Switzerland 4 Institute for Biomedical Engineering, University and ETH Zurich, 8091 Zurich, Switzerland 5 Zurich Centre for Integrative Human Phy...

Pancreatic cancer is one of the most lethal malignancies worldwide. To illustrate the pathogenic mechanism(s), we looked into the expression and function of miR-329 associated with pancreatic cancer development. It was found that miR-329 expression was downregulated in the pancreatic cancer patients who demonstrated significantly shorter overall survival than the patients having upregulated exp...

The influence of dietary supplementation with dehydroepiandrosterone-sulphate (DHEA-S) at 0.6% was investigated in male Syrian golden hamsters initiated by treatments with azoxymethane(AOM), and dihydroxy-di-n-propyl nitrosamine (DHPN), timed after transfer from a choline-deficient to a normal diet. These carcinogens respectively target the colon, and the respiratory tract, the liver and pancre...

Gastric cancer (GC) is one of the most common malignant tumors worldwide. Emerging evidence has shown that abnormal microRNAs (miRNAs) expression is involved in tumorigenesis. MiR-329 was previously reported to act as a tumor suppressor or oncogene in some types of cancer. However, its function in gastric cancer (GC) is unclear. Here, we found that miR-329 was down-regulated in GC compared with...

MicroRNAs (miRNAs) act as key regulators of multiple cancers. Hsa-miR-329 (miR-329) functions as a tumor suppressor in some malignancies. However, its role on lung cancer remains poorly understood. In this study, we investigated the role of miR-329 on the development of lung cancer. The results indicated that miR-329 was decreased in primary lung cancer tissues compared with matched adjacent no...