Legg-Calve-Perthes disease (LCPD) is a type of avascular necrosis of the femoral head occurring mainly in male children and causing early osteoarthritis. We report 2 generations of 4 male family members with LCPD-like features and mutation of the COL2A1 gene of the 12q13 chromosome. If LCPD occurs in any family member, we recommend genetic analysis and counselling as well as early radiological ...

Meyer's dysplasia strongly mimics Legg-Calve-Perthes' disease despite differing markedly in eventual outcome. This study presents the clinicoradiologi-cal features which differentiate it from Perthes' disease in a group of 178 children with a preliminary diagnosis of Perthes' disease, of whom nine were subsequently diagnosed with Meyer's dysplasia. All had a near normal development of the femor...

  Background: Legg-Calve´-Perthes disease is a juvenile idiopathic osteonecrosis in which the blood supply of femoral head is not sufficient and the bone dies provisionally. The aim of this study is to evaluate outcome of Femoral osteotomy in children with LCPD in our University Hospital.   Methods: In a descriptive analytic study, between 2008 and 2013, patients with the diagnosis of Legg-Calv...

Thirty-two patients (out of 52 undergoing surgery) with Legg-Calvé-Perthes disease (LCP) were examined retrospectively to assess the efficacy of surgical treatment on epiphyseal morphology at the primary healing. The analysis of the clinical results of the 33 hips considered indicated that it is necessary to operate above all on 3rd grade hips. For these the most frequent operation indicated is...

INTRODUCTOIN: Legg-Calve-Perthes disease (LCPD) is a common juvenile form of ischemic osteonecrosis of the femoral head that affects children between the ages of 2 to 14 years and has the attack rate of 1 in 740 boys and 1 in 3700 girls. LCPD is due to blood supply disruption to the femoral head. Ischemic osteonecrosis of the femoral head remains one of the most challenging conditions to treat ...